Publications by authors named "Yi-Chu Yuan"
Objectives: To describe the influence of the socioeconomic development on worldwide age-standardized incidence and mortality rates, as well as mortality-to-incidence ratio (MIR) and 5-year net survival of urologic cancer patients in recent years.
Methods: The Human Development Index (HDI) values were obtained from the United Nations Development Programme, data on age-standardized incidence/mortality rates of prostate, bladder and kidney cancer were retrieved from the GLOBOCAN database, 5-year net survival was provided by the CONCORD-3 program. We then evaluated the association between incidence/MIR/survival and HDI, with a focus on geographic variability as well as temporal patterns during the last 6 years.
Article Synopsis
- A new analytical method combining hydrophilic interaction ultra-performance liquid chromatography and mass spectrometry (HILIC-UHPLC-QTRAP®/MS) was developed to analyze neurotransmitters in urine samples of patients with varying stages of dementia.
- The method utilizes ultrasound-assisted ionic liquid microextraction (UA-IL-DLLME) to efficiently prepare samples, with optimized conditions for extraction established through experimental design.
- Findings indicated significant variations in neurotransmitters like GABA, acetylcholine, and glutamic acid across different dementia stages, suggesting their potential as biomarkers for diagnosis and classification of dementia.