Publications by authors named "Yi-Cheng Xiao"

Ergosta-7, 9 (11), 22-trien-3β-ol (EK100) was isolated from , which has been used as a traditional anti-inflammatory medicine. EK100 has been reported to attenuate inflammatory diseases, but its anti-inflammatory mechanism is still unclear. We were the first to investigate the effect of EK100 on the Toll-like receptor 4 (TLR4)/nuclear factor of the κ light chain enhancer of B cells (NF-κB) signaling in the lipopolysaccharide (LPS)-stimulated RAW264.

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Article Synopsis
  • Two types of articular cartilage defect models (A and B) were created using adult New Zealand white rabbits, each repaired with different composite scaffolds for comparison.
  • Group A utilized scaffolds with seed cells, while Group B used scaffolds without seed cells, both incorporating gum-bletilla and Pluronic F-127.
  • Post-surgery evaluations at 4, 12, and 24 weeks showed successful cartilage repair in both groups, with gum-bletilla proving essential for enhanced healing outcomes.
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