Ergosta-7, 9 (11), 22-trien-3β-ol (EK100) was isolated from , which has been used as a traditional anti-inflammatory medicine. EK100 has been reported to attenuate inflammatory diseases, but its anti-inflammatory mechanism is still unclear. We were the first to investigate the effect of EK100 on the Toll-like receptor 4 (TLR4)/nuclear factor of the κ light chain enhancer of B cells (NF-κB) signaling in the lipopolysaccharide (LPS)-stimulated RAW264.
View Article and Find Full Text PDFZhongguo Zhong Yao Za Zhi
February 2018