Publications by authors named "Yi-Bo Tong"
Article Synopsis
- Enhancers are important factors in cancer research for diagnostics and treatment, but analyzing them is challenging due to a lack of comprehensive data from tumor tissues.
- To address this, researchers created CenhANCER, a database compiling extensive data on enhancers from 805 primary tissue and 671 cell line samples across 41 cancer types.
- The database includes over 57 million typical enhancers and 978,411 super-enhancers, with accompanying annotations for further analysis, providing a valuable resource for studying cancer enhancers and potential therapeutic targets.
The origination of new genes contributes to the biological diversity of life. New genes may quickly build their network, exert important functions, and generate novel phenotypes. Dating gene age and inferring the origination mechanisms of new genes, like primate-specific genes, is the basis for the functional study of the genes.
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