Publications by authors named "Yi-Bin Shen"
Article Synopsis
- The study aimed to investigate the relationship between recurrent laryngeal nerve (RLN) invasion and lymph node metastasis in patients with papillary thyroid carcinoma (PTC), highlighting that RLN involvement increases recurrence risk and informs surgical decisions.
- Retroactively reviewing 130 PTC patients, the researchers compared outcomes and clinicopathologic features related to solitary versus multiple RLN invasions, utilizing follow-up data and various statistical analyses to assess recurrence risk factors.
- Results showed similar patterns of RLN invasion, noteworthy associations with tumor size and lymph node metastasis, and identified a tumor size of greater than 1.7 cm as a significant predictor for multiple RLN involvements or lymph node metastasis.
SYT7 plays a role in promoting thyroid cancer by mediating HMGB3 ubiquitination.
Endocr Relat Cancer
March 2022
Thyroid cancer is one of the most common endocrine malignancies. It is necessary to discover more effective molecular targets for the treatment of thyroid cancer. The results of immunohistochemical staining, qPCR and Western blot indicated that the expression of SYT7 in thyroid cancer tissues and cells was higher than that in paracarcinoma tissues and normal thyroid cells.
View Article and Find Full Text PDFPurpose: The relationship between large thyroid nodules and the risk of malignancy is controversial. This study aimed to examine the relationship between thyroid nodule size and the risk of malignancy of maximal thyroid nodules ≥2 cm and the risk of accompanied by occult thyroid carcinoma.
Methods: This was a retrospective study of patients who underwent near-total or total thyroidectomy for thyroid nodules from January 2016 to January 2019 at the First Affiliated Hospital,Zhejiang University School of Medicine.
Background: Hypothyroidism is a common hormone deficiency condition. Regenerative medicine approaches, such as a bioengineered thyroid, have been proposed as potential therapeutic alternatives for patients with hypothyroidism. This study demonstrates a novel approach to generate thyroid grafts using decellularized rat thyroid matrix.
View Article and Find Full Text PDFThe purpose of this study was to investigate the risk factors for central and lateral neck lymph node metastases in papillary thyroid carcinoma (PTC) and multifocal papillary thyroid carcinoma (MPTC), particularly when associated with Hashimoto thyroiditis (HT).A retrospective analysis of 763 consecutive patients who underwent total thyroidectomy with bilateral central neck dissection in the First Affiliated Hospital, College of Medicine, Zhejiang University between October 2011 and October 2014 was conducted. All patients had formal histological diagnoses of HT.
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