Construction and Physical Mapping of the 35 cM YAC Contigs for the Region of Xp11.2 - p21.3.

One hundred and fifty-one YACs were selected from three libraries with a series of STS and other DNA probes of the human X chromosome p11.2 - p21.3 region.

A 4.3 Mb YAC Contig in Human Xp11.2: Long-Range Restriction Mapping and Identification of CpG Islands.

The Xp11.2 region o the human X chromosome contains genes involved in a number of inherited diseased, with at least one locus that escapes X chromosome inactivation, as well as abnormal methylation polymorphism. We isolated a series of yeast artificial chromosome (YAC) clones by hybridization screening with DNA probes localized within this region and assembled them into a 4.