Publications by authors named "Yi-An Hu"

Article Synopsis
  • Echocardiography is widely used to evaluate hydration and cardiac function in kidney failure patients, and this study explored the prevalence and significance of echocardiographic abnormalities in this population.* -
  • Out of 857 kidney failure patients, 77% showed echocardiographic abnormalities, with left ventricular hypertrophy being most common; however, key predictors of adverse cardiovascular events and mortality were related to left ventricular function and volume rather than these abnormalities.* -
  • The study's findings suggest that specific heart functions, especially left ventricular issues, are crucial for predicting outcomes in kidney failure patients, which can guide better patient management strategies.*
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The type 2 transmembrane serine protease matriptase is broadly expressed in human carcinomas and hematological cancers. The proteolytic activity of matriptase is a potential target of drugs and imaging probes. We assessed the fate of active matriptase following the induction of matriptase zymogen activation.

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