Publications by authors named "Yi Ying Teo"
Pharmacogenomics
October 2024
Article Synopsis
- The study reviews the impact of single nucleotide polymorphisms (SNPs) on how allopurinol is processed in the body to manage uric acid levels.
- A thorough search of databases led to 17 relevant articles that identified 11 significant SNPs affecting the pharmacokinetics of both allopurinol and its active form, oxypurinol.
- Certain SNPs linked to specific genes were found to influence allopurinol clearance and its metabolism, along with their potential roles in the regulation of uric acid levels, although some results were inconsistent across different studies.
