Publications by authors named "Yi Yan Qiu"
Article Synopsis
- Long non-coding RNA MEG3 is implicated in osteoporosis development and interacts with microRNA-214 and thioredoxin-interacting protein (TXNIP).
- Rat models were used to examine the effects of MEG3 on bone density and osteoblast functionality, showing that silencing MEG3 and overexpressing miR-214 improved various bone health metrics.
- The study findings suggest that MEG3 regulates osteoblast proliferation and differentiation through its connection with miR-214 and TXNIP, providing insights into potential therapeutic strategies for osteoporosis.
MicroRNAs (miRNAs) have been corroborated to engage in the process of cellular activities in osteoporosis. However, few researches have been conducted to expose the integrated role of miR-497, leucine-rich alpha-2-glycoprotein-1 (LRG1) and transforming growth factor beta 1 (TGF-β1)/Smads signalling pathway in osteoporosis. Thereafter, the study is set out to delve into miR-497/LRG1/TGF-β1/Smads signalling pathway axis in osteoporosis.
View Article and Find Full Text PDFObjective: The purpose of this meta-analysis of randomized controlled trials (RCTs) and non-RCTs was to gather data to evaluate the efficacy and safety of bipolar sealer versus standard electrocautery in the management of spinal disease.
Methods: The electronic databases including Embase, PubMed and Cochrane library were searched to identify relevant studies published from the time of the establishment of these databases up to January 2017. The primary outcomes were total blood loss, requirement of transfusion (rate and amount), and operation time.
Objective: To assess the early curative effect of epidural or intravenous administration of steroids during a percutaneous endoscopic lumbar discectomy (PELD).
Methods: 28 consecutive patients who underwent PELD due to large lumbar disc herniation between November 2014 and January 2016 were followed up for 6 months. These patients were divided into two groups according to the treatment they received after PELD.
Purpose: To investigate the usefulness of three-dimensional (3D) printing in complex spinal surgery.
Methods: The study was conducted from October 2014 to March 2015 in Shenzhen Second Peoples' Hospital and 4 cases of complex severe spinal disorders were selected from our department. Among them one patient combined with congenital scoliosis, one with atlas neoplasm, one with atlantoaxial dislocation, and the rest one with atlantoaxial fracture-dislocation.
Review article: Treatments for bone loss in revision total knee arthroplasty.
J Orthop Surg (Hong Kong)
April 2012
Article Synopsis
- Bone deficiency can cause issues with aligning and stabilizing implants in revision total knee arthroplasty (TKA).
- Different treatments for these bone defects vary based on their size and location, including options like cement, metal augments, and allografts.
- Recent advancements have introduced porous tantalum as a promising material for managing these defects, and a review of the advantages and disadvantages of each method was conducted.
Review article: bone defect classifications in revision total knee arthroplasty.
J Orthop Surg (Hong Kong)
August 2011
Article Synopsis
- There are multiple classification systems for bone defects in revision total knee arthroplasty, but each has its limitations.
- None of the existing systems fully meets all clinical needs for treatment.
- A new classification system and treatment guidelines are needed, considering factors like location, side, containment, and severity of the bone defects.