A greater glycemic load reduction was associated with a lower diabetes risk in pre-diabetic patients who consume a high glycemic load diet.

Few prospective studies evaluating the association between dietary glycemic load (GL) and diabetes have accounted for changes in GL. However, the diet of patients could be modified in response to an awareness of pre-diabetes. The aim of this study was to examine the longitudinal associations between changes in GL and the incidence of diabetes among pre-diabetic patients.

Association between obesity measures and albuminuria: A population-based study.

Aims: The effects of obesity on the micro vascular diseases have drawn much attention. The aim of the study was to investigate the relationship between obesity measures and albuminuria in Chinese population.

Methods: We conducted a population-based cross-sectional study in 8600 subjects aged 40 years or older from a community in Guangzhou.

Prevention of macrovascular disease in patients with short-duration type 2 diabetes by multifactorial target control: an 8-year prospective study.

A longitudinal prospective study was undertook to investigate the effect of multifactorial target control, recommended by the American Diabetes Association (ADA), on macrovascular disease in patients with short-duration type 2 diabetes. Patients who were newly diagnosed with type 2 diabetes or within 1 year and had no previous vascular diseases or atherosclerosis plaques were enrolled in the present study. All patients received multifactorial intervention, with pharmacologic therapy targeting hyperglycemia, hypertension, dyslipidemia, along with secondary prevention of vascular disease with aspirin when necessary according to the ADA recommendation.

[Insulin sensitivity and pancreatic beta cell function changes during the transformation from normal to impaired glucose tolerance].

Objective: To investigate the roles of insulin sensitivity and pancreatic beta cell function in the pathogenesis of type 2 diabetes.

Methods: 70 subjects were recruited in a 3-year prospective study. During this period 9 subjects progressed from normal glucose tolerance (NGT) to impaired glucose tolerance (IGT) (progressing group), 45 remained same (remaining group) and 16 improved from IGT to NGT (improving group).

[A multicenter clinic study of slow-release-gliclazide in type 2 diabetes mellitus].

Objective: To evaluate the efficacy and safety of 30 mg slow-release-gliclazide (Diamicron MR) on type 2 diabetes patients with the level of blood glucose poorly controlled formerly.

Methods: 154 type 2 diabetes patients with the level of blood glucose poorly controlled formerly were enrolled and treated with Diamicron MR for 16 weeks. The efficacy of slow-release-gliclazide was evaluated through HbA1c, FPG and 2 h PBG after 16 weeks of treatment period.