RIS-assisted optical receiver model and reflected angle optimization for visible light communication in mobile environments.

Reconfigurable intelligent surfaces (RIS) supply high-speed and in-depth coverage wireless networks for visible light communication (VLC) systems, improving the system adaptability to mobile scenarios. But the angle-related efficiency loss caused by the diffraction effect of RIS as well as the angular response of the lens-enhanced optical receiver severely affects the practical performance of the RIS-assisted VLC system, which have not draw the attention of researchers. By the influences of these adverse properties, the beam angle configuration method should be further explored.

Equivalent analysis model of a GaN LED used as a receiver.

In general, visible light communication (VLC) uses LEDs as transmitters. However, LEDs can serve as receivers to construct a simple duplex VLC system that uses only two LEDs instead of one LED and one photo-diode (PD). There is a lack of effective equivalent analysis models for characterizing and evaluating the inherent behavioral characteristics of LEDs used as receivers.

Combinatorial expression of γ-protocadherins regulates synaptic connectivity in the mouse neocortex.

In the process of synaptic formation, neurons must not only adhere to specific principles when selecting synaptic partners but also possess mechanisms to avoid undesirable connections. Yet, the strategies employed to prevent unwarranted associations have remained largely unknown. In our study, we have identified the pivotal role of combinatorial clustered protocadherin gamma (γ-PCDH) expression in orchestrating synaptic connectivity in the mouse neocortex.

RIS-aided dynamically adaptive wide field-of-view receiver for visible light communication in industrial internet of things.

In the current visible light communication (VLC) system, a condenser lens is generally used in the front of receiver to achieve a higher data rate, making an extremely narrow field-of-view for the receiver. With the spread of Industrial Internet of Things (IIoT), the communication between mobile terminals is urgently required. A wide-range detecting method for VLC system in IIoT scenario is asked.

Bloodstream infection caused by Solobacteriummoorei: A case report and literature review.

Solobacterium moorei is an asporogenous, strictly anaerobic, short-to-long bacillus belonging to the family Erysipelotrichidae and phylum Firmicutes. This bacterium rarely causes bloodstream infections. Here, we report a case of the postoperative recurrence and metastasis of gastric antral adenocarcinoma combined with S.

Characterization of Epoxy-Based Rapid Mold with Profiled Conformal Cooling Channel.

Based on the experience of the foundry industry, reducing the demolding time is the key for mass production of wax patterns with sophisticated geometries. Integration of numerical simulation and rapid tooling technology for decreasing the time to market is essential in advanced manufacturing technology. However, characterization of epoxy-based rapid molds with a profiled conformal cooling channel (PCCC) using computer-aided engineering simulation of the epoxy-based rapid mold with PCCC was not found in the literature.

A developmental switch between electrical and neuropeptide communication in the ventromedial hypothalamus.

Dissecting neural connectivity patterns within local brain regions is an essential step to understanding the function of the brain. Neural microcircuits in brain regions, such as the neocortex and the hippocampus, have been extensively studied. By contrast, the microcircuit in the hypothalamus remains largely uncharacterized.

Effects of Different Mold Materials and Coolant Media on the Cooling Performance of Epoxy-Based Injection Molds.

Metal additive manufacturing techniques are frequently applied to the manufacturing of injection molds with a conformal cooling channel (CCC) in order to shorten the cooling time in the injection molding process. Reducing the cooling time in the cooling stage is essential to reducing the energy consumption in mass production. However, the distinct disadvantages include higher manufacturing costs and longer processing time in the fabrication of injection mold with CCC.

Rapid Development of an Injection Mold with High Cooling Performance Using Molding Simulation and Rapid Tooling Technology.

Rapid tooling technology (RTT) provides an alternative approach to quickly provide wax injection molds for the required products since it can reduce the time to market compared with conventional machining approaches. Removing conformal cooling channels (CCCs) is the key technology for manufacturing injection mold fabricated by rapid tooling technology. In this study, three different kinds of materials were used to fabricate CCCs embedded in the injection mold.

Correlation of lower 2 h C-peptide and elevated evening cortisol with high levels of depression in type 2 diabetes mellitus.

Background: A number of studies have explored the association between depression and ghrelin, leptin, and cortisol; further, postprandial C-peptide levels have a therapeutic effect on type 2 diabetes mellitus (T2DM). However, the relationship between C-peptide and depression in patients with diabetes, remains unclear. The aim of this study was to explore the association between depression and ghrelin, leptin, cortisol, and C-peptide in patients with diabetes.

A novel mutation causes autosomal dominant cataract: A report from a Chinese family.

Purpose: This study aimed to examine pathogenic mutation within one Chinese family of five-generations suffering from autosomal dominant cataract.

Methods: Next-generation sequencing and Sanger sequencing were used to find the pathogenic variants.

Results: A rare mutation, c.

Adaptive spatial-layout selection for massive multi-color visible light communications.

Massive multi-color visible light communications (mMC-VLC) sufficiently utilizing space and color domain resources is proposed to satisfy high-spectral-efficiency, high-speed, and high-density-coverage requirements of next-generation indoor data connections. However, the gap between the number of LEDs and photodiodes (PDs) and the high correlation among different channels limit the multiplexing of mMC-VLC. Also, the mobility of the receiver is the bottleneck of mMC-VLC.

Fast-adaptive color-collaborative constellation designs for multicolor multiple-input multiple-output visible light communications systems.

A fast-adaptive color-collaborative signal constellation (CCSC) is proposed for chromaticity-changeable multicolor multiple-input multiple-output (MIMO) visible light communications (VLC) systems. The design of CCSC aims at developing the constellation to minimize the average optical power with shaping-based lattice code. For multicolor VLC signals, we arrive at the fact that the optimum shape of the constellation bounding region is an inequilateral N-D simplex.

One symbol training receiver for the SPAD-based UVLC system.

For the long distance single photon avalanche diode (SPAD)-based underwater visible light communication (UVLC) system, the multiple-symbol union detection scheme is presented. However, an error floor curve of the bit-to-error ratio (BER) occurs and cannot vanish even though the transmitted power approaches infinity. In this paper, to solve the problems of error floor and channel estimation in the long distance SPAD-based UVLC system, we propose the one training symbol maximum likelihood (ML) detection receiver.

The association of short-term memory and cognitive impairment with ghrelin, leptin, and cortisol levels in non-diabetic and diabetic elderly individuals.

Aims: This study assessed short-term memory and biochemical indicators with the levels of ghrelin, leptin, and cortisol between cognitive impairment and normal older adults with or without diabetes.

Methods: We enrolled 286 older adults (aged 65-85 years) with or without diabetes from the local community. Short-term memory was assessed using pictures of common objects; cognitive functioning was assessed using the Mini-Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA).

Efficient signal design and optimal power allocation for visible light communication attocell systems.

In this paper, we investigate visible light communication (VLC) attocell systems in which any two neighboring attocells overlap. An efficient signal design for VLC called time superposition reuse (TSR) is proposed to mitigate interference and improve spectral efficiency. In the scheme, two neighboring cells are allocated with two time slots that have superposition in the time domain.

Interferon-γ suppresses the proliferation and migration of human placenta-derived mesenchmal stromal cells and enhances their ability to induce the generation of CD4CXCR5Foxp3Treg subset.

We investigate the effects of interferon (IFN)-γ on human placenta-derived mesenchymal stromal cells (hPMSCs), in particular, their adhesion, proliferation and migration and modulatory effects on the CD4CXCR5Foxp3Treg subset. And we compared hPMSCs ability to induce the generation of different Treg subsets in response to treatment with IFN-γ. We found that IFN-γ suppressed the proliferation and migration for hPMSCs.

Changes in the Level of Immunoglobulins and CD4/CD8 Ratio in Young and Aged Mice with Estradiol Deficiency.

Studies demonstrated that deficiency in 17β-estradiol (E) in postmenopausal women influences their immune system. However, few studies have reported alterations in immunologic presentation during nonnatural menopause in young females. Here we compared the differences in immune response between young C57BL/6N mice with surgical or medical variectomy and aged C57BL/6N mice with the common feature of E deficiency following Con A stimulation.

Correction: Cardiomyocyte-Specific Ablation of Med1 Subunit of the Mediator Complex Causes Lethal Dilated Cardiomyopathy in Mice.

[This corrects the article DOI: 10.1371/journal.pone.

Cardiomyocyte-Specific Ablation of Med1 Subunit of the Mediator Complex Causes Lethal Dilated Cardiomyopathy in Mice.

Mediator, an evolutionarily conserved multi-protein complex consisting of about 30 subunits, is a key component of the polymerase II mediated gene transcription. Germline deletion of the Mediator subunit 1 (Med1) of the Mediator in mice results in mid-gestational embryonic lethality with developmental impairment of multiple organs including heart. Here we show that cardiomyocyte-specific deletion of Med1 in mice (csMed1-/-) during late gestational and early postnatal development by intercrossing Med1fl/fl mice to α-MyHC-Cre transgenic mice results in lethality within 10 days after weaning due to dilated cardiomyopathy-related ventricular dilation and heart failure.

Diversity-optimal power loading for intensity modulated MIMO optical wireless communications.

In this paper, we consider the design of space code for an intensity modulated direct detection multi-input-multi-output optical wireless communication (IM/DD MIMO-OWC) system, in which channel coefficients are independent and non-identically log-normal distributed, with variances and means known at the transmitter and channel state information available at the receiver. Utilizing the existing space code design criterion for IM/DD MIMO-OWC with a maximum likelihood (ML) detector, we design a diversity-optimal space code (DOSC) that maximizes both large-scale diversity and small-scale diversity gains and prove that the spatial repetition code (RC) with a diversity-optimized power allocation is diversity-optimal among all the high dimensional nonnegative space code schemes under a commonly used optical power constraint. In addition, we show that one of significant advantages of the DOSC is to allow low-complexity ML detection.

Interleukin-1B 31 C>T polymorphism combined with Helicobacter pylori-modified gastric cancer susceptibility: evidence from 37 studies.

Gastric cancer is one of the most common malignancies worldwide. Interleukin-1-beta (IL-1β) is a pro-inflammatory cytokine and potent inhibitor of gastric acid secretion. Some studies provided evidence of the association between IL-1B 31 polymorphism and gastric cancer risk while other studies did not.

Energy-efficient space-time modulation for indoor MISO visible light communications.

We consider an indoor multi-input single-output (MISO) visible light communication (VLC) system without channel state information at the transmitter. For such a system, an energy-efficient time-collaborative modulation (TCM) constellation is first designed by minimizing a total optical power subject to a fixed minimum Euclidean distance. Then, a new space-time transmission scheme is proposed.

PPARα-Deficient ob/ob Obese Mice Become More Obese and Manifest Severe Hepatic Steatosis Due to Decreased Fatty Acid Oxidation.

Obesity poses an increased risk of developing metabolic syndrome and closely associated nonalcoholic fatty liver disease, including liver cancer. Satiety hormone leptin-deficient (ob/ob) mice, considered paradigmatic of nutritional obesity, develop hepatic steatosis but are less prone to developing liver tumors. Sustained activation of peroxisome proliferator-activated receptor α (PPARα) in ob/ob mouse liver increases fatty acid oxidation (FAO), which contributes to attenuation of obesity but enhances liver cancer risk.