Publications by authors named "Yi Jun Han"
Coenzyme Q10 (CoQ10) is an essential medicinal ingredient. In this study, we obtained a high-yielding mutant strain of CoQ10, VK-2-3, by subjecting V-0 (V-0) to a C heavy ion beam and high-voltage prick electric field treatment. To investigate the mutation mechanism, the complete genomes of VK-2-3 and V-0 were sequenced.
View Article and Find Full Text PDF[Comparison of clinical and immunological characteristics between primary Sjögren's syndrome patients with positive and negative anti-SSB antibody].
Beijing Da Xue Xue Bao Yi Xue Ban
December 2023
Article Synopsis
- The study aimed to compare clinical and lab features of primary Sjögren's syndrome (pSS) patients based on their anti-SSB antibody status.
- A total of 142 pSS patients were analyzed, revealing that those with positive anti-SSB antibodies were generally younger and had more specific symptoms like rash and parotid gland enlargement.
- The anti-SSB positive group also showed higher levels of certain antibodies and proteins like rheumatoid factor and IgG, but they were less likely to test positive for anti-mitochondrial antibodies.
Coenzyme Q10 (CoQ10) plays an important role in the human respiratory chain and is widely used as medicine and dietary supplement. To improve the fermentation efficiency of CoQ10, a modified version of atmospheric and room temperature plasma (ARTP) treatment was used to mutate Rhodobacter sphaeroides. Meanwhile, Vitamin K3, a structural analog of CoQ10, was used as an inhibitor for mutant selection.
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