Synopsis of recent research by authors named "Yeyun Kim"
- Yeyun Kim's recent research explores the genetic and epigenetic mechanisms underlying neurodegenerative disorders, particularly focusing on the impact of enhancer mutations on neuronal mitochondria dysfunction and motor deficits in mice.
- The studies identify key genetic markers, such as the ALS-associated SNP (rs304152), within non-coding regions that influence epigenetic modifications, shedding light on the complex pathology of neurodegenerative diseases.
- Additionally, Yeyun Kim investigates the role of astrocytic autophagy in Alzheimer's disease, revealing how Aβ-induced proteotoxic stress affects autophagy gene expression and modulates Aβ clearance, contributing to insights into neuroprotective strategies.