Results of intravitreal dexamethasone implant 0.7 mg (Ozurdex®) in non-infectious posterior uveitis.

Aim: To evaluate the safety and efficacy of dexamethasone implant in patients with non-infectious posterior uveitis with cystoid macular edema (CME).

Methods: Retrospective analysis of patients reports with CME secondary to non-infectious uveitis treated with dexamethasone implant. Data included type of posterior uveitis, any systemic immunosuppressive therapy, Early Treatment Diabetic Retinopathy Study (ETDRS) best-corrected visual acuity (BCVA), central macular thickness (CMT) on optical coherence tomography (OCT) and signs of intraocular inflammation at baseline and then at 2wk postoperatively and monthly thereafter.

Central retinal vein occlusion secondary to protein S deficiency.

We present a case of protein S deficiency causing central retinal vein occlusion treated with anticoagulation, which includes heparin followed by oral warfarin therapy. This article highlights the importance of looking for other possible causes of central retinal vein occlusion, especially in younger patients with negative initial investigations.

A serious pain in the neck.

We describe a case of internal carotid artery dissection, an important cause of ischemic cerebrovascular disease. Presentations include a headache, which is usually unilateral to the side of carotid dissection, sharp, nonthrobbing in nature with radiation from the neck. The clinical presentations, investigations, and treatment of the disease are discussed.

Descemetocoele from exposure keratopathy.

We present a case of descemetocoele secondary to facial nerve palsy causing exposure keratopathy. To prevent further ocular morbidity, a central tarsorrhaphy was performed. On follow-up two weeks later, no further deterioration of the eye was detected.

Cavernous sinus syndrome secondary to metastasis from small cell lung carcinoma.

We report a case of cavernous sinus syndrome presenting with painful trigeminal neuropathy secondary to metastasis from a small cell lung carcinoma, which responded to radiotherapy.

Follicular lymphoma involving the orbit.

Non-Hodgkin's lymphoma is the fifth most common malignancy, with an annual incidence in the UK of 8/100,000. Until recently this incidence had been rising over the past two decades. The WHO classification divides non-Hodgkin's lymphomas into B- or T-cell neoplasms, with 85% of general lymphomas and almost all orbital lymphomas consisting of B-cell tumours.