Modern 3D printing of implantable devices provides an important opportunity for the development of personalized implants with good anatomical fit. Nevertheless, 3D printing of silicone has been challenging and the recent advances in technology are provided by the systems which can print medical grade silicone via extrusion. However, the potential impacts of the 3D printing process of silicone on its biomechanical properties has not been studied in sufficient detail.
View Article and Find Full Text PDFPrevention of bacterial inflammation around dental implants (peri-implantitis) is one of the keys to success of the implantation and can be achieved by securing the gingival tissue-abutment interface preventing penetration of bacteria. Modern dental practice has adopted zirconia abutments in place of titanium, but the adhesion of gingival tissue to zirconia is inferior to titanium. The aim of this study was to assess and improve the adhesion of mucosal tissues to zirconia posts using sol-gel derived TiO coating following dynamic mechanical testing.
View Article and Find Full Text PDFNanofibrous substrates and scaffolds are widely being studied as matrices for 3D cell cultures, and disease models as well as for analytics and diagnostic purposes. These scaffolds usually comprise randomly oriented fibers. Much less common are nanofibrous scaffolds made of stiff inorganic materials such as alumina.
View Article and Find Full Text PDFScaffolds for articular cartilage repair have to be optimally biodegradable with simultaneous promotion of hyaline cartilage formation under rather complex biomechanical and physiological conditions. It has been generally accepted that scaffold structure and composition would be the best when it mimics the structure of native cartilage. However, a reparative construct mimicking the mature native tissue in a healing tissue site presents a biological mismatch of reparative stimuli.
View Article and Find Full Text PDFJ Mech Behav Biomed Mater
February 2014
Use of hydroxyapatite (HAP) for biomaterials is widely established, often in a combination with titanium alloy substrates in orthopaedic and other implants. Porous HAP-based coatings undergo sintering and heat treatment processes to achieve proper level of density yet avoiding undesirable reactions and phase changes. Thermal expansion mismatch between constituents may also lead to cracking of the coating due to excessive thermal stresses.
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