Development and assessment of the disposition index based on the oral glucose tolerance test in subjects with different glycaemic status.

Insulin secretion and insulin sensitivity indexes are related by hyperbolic functions, allowing the calculation of the disposition index (DI) as the product of the acute insulin response (AIR) and the insulin sensitivity index (Si) from intravenous glucose tolerance test (IVGTT). Our objective was to develop an oral-DI based on the oral glucose tolerance test (OGTT) and to assess its association with glucose tolerance status. This research is structured in three studies.

Salivary Urease and ADS Enzymatic Activity as Endogenous Protection against Dental Caries in Children.

Unlabelled: The aim of this cross sectional study was to evaluate the ureolytic and arginolytic activities of saliva in children and associate them with their caries status.

Study Design: 65, 8 year old children, were randomly selected. The ureolytic and arginolytic activity of non stimulated saliva was studied and associated with DMFT and dmft index.

Caries-free subjects have high levels of urease and arginine deiminase activity.

Objectives: This study investigated the relationship between urease and arginine deiminase system (ADS) activities and dental caries through a cross-sectional study.

Material And Methods: Urease and ADS activities were measured in saliva and plaque samples from 10 caries-free subjects and 13 caries-active. Urease activity was obtained from the ammonia produced by incubation of plaque and saliva samples in urea.

[Absorption of fluorides by synthetic hydroxyapatites].

We studied the adsorption of sodium fluoride, ammonium fluoride, tin fluoride and sodium monofluorophosphate to synthetic hydroxiapatite in function of the pH (pH 4.7, 5.5 and 6.

Effects of Loxosceles laeta spider venom on blood coagulation.

The hematologic effects of intradermal injection of Loxosceles laeta venom in rabbits were studied with special reference to partial thromboplastin time, prothrombin time, platelet count and fibrinogen-fibrin degradation products. The in vitro effect of Loxesceles laeta venom on human platelet aggregation was also studied. Fibrinogen and platelet count decreased and fibrinogen-fibrin degradation products increased at 12 hr.