Synopsis of recent research by authors named "Yeun Joo Choi"
- Yeun Joo Choi's recent research focuses on the interplay between microRNAs and mRNAs in the regulation of circadian rhythms, demonstrating specific target pairs with circadian expression patterns.
- The findings indicate that certain microRNAs, such as miR-181d and miR-191, exhibit inverse expression patterns relative to circadian initiators Clock and Bmal1, suggesting a regulatory feedback loop.
- Additionally, Choi has contributed to understanding genetic mutations in neurodegenerative disorders, identifying a missense mutation in the SPG4 gene associated with autosomal-dominant hereditary spastic paraplegia in a specific familial case in Korea.
