A novel iridium(III) complex-based ratiometric luminescence probe for monitoring hydrogen sulfide in living cells and zebrafish.

Hydrogen sulfide exhibits crucial functions in many biological and physiological processes. The abnormal levels of HS have been revealed to be associated with numerous human diseases. The majority of existing fluorescent probes toward HS may still need to be improved in terms of single output signal, water solubility, biotoxicity and photostability.

Ultrasensitive detection of butyrylcholinesterase activity based on the inner filter effect of MnO nanosheets on sulfur nanodots.

Butyrylcholinesterase (BChE) activity is an important index for a variety of diseases. In this work, a "turn-on" assay is proposed based on controlling the inner filter effect (IFE) of MnO nanosheets (NSs) on sulfur nanodots (S-dots). The fluorescence of S-dots is effectively quenched by the MnO NSs, due to the wide overlap of the emission spectrum of S-dots and absorption spectrum of MnO NSs, together with the superior light absorption capability of MnO NSs.