Can spinal bupivacaine analgesia treatment make a difference on urinary bladder healing according to the intramuscular pethidine analgesia treatment in rats?

We designed a study to compare the healing levels found with intramuscular pethidine with those found with intrathecal local anesthetic treatments. The urinary bladder is suggested to be the most useful tissue in the evaluation of the effects of the drugs. Nineteen male, Sprague-Dawley rats weighing 200 C300 g were used in this study.