Shift work and non-alcoholic fatty liver disease in young, healthy workers.

Non-alcoholic fatty liver disease (NAFLD) is a relatively common disease, and preventing its occurrence is important for both individual health and reducing social costs. Shift work is reported to have several negative effects on health. An association has been observed between NAFLD and both sleep time and quality; however, this association remains unclear in night shift workers.

Association between shift work and the risk of hypothyroidism in adult male workers in Korea: a cohort study.

Background: Shift work has been reported to have several harmful effects on the human body. However, a small number of studies have evaluated the association between shift work and adverse effects on the thyroid. In our longitudinal study, we examined the causal association between shift work and the risk of hypothyroidism.

Association between hearing loss and high-sensitivity C-reactive protein: the Kangbuk Samsung Cohort Study.

Background: Hearing loss (HL) is linked to an elevated risk of cardiovascular diseases (CVDs). The pathogeneses of HL and CVD commonly involve inflammatory responses. Previous studies investigated elevated levels of inflammatory biomarkers in subjects with HL, however, their findings did not demonstrate statistical significance.

Determinants of overall survival in patients with metastatic uveal melanoma.

Background: Despite improvements in the treatment of primary uveal melanoma (UM), patients with metastatic disease continue to exhibit poor survival.

Methods: A retrospective review of metastatic UM patients at Yale (initial cohort) and Memorial Sloan Kettering (validation cohort) was conducted. Cox proportional hazards regression was used to determine baseline factors that are associated with overall survival, including sex, Eastern Cooperative Oncology Group (ECOG) Performance Status Scale, laboratory measurements, metastasis location, and use of anti-CTLA-4 and anti-PD-1 therapies.

The association between shift work and the incidence of reflux esophagitis in Korea: a cohort study.

Shift work has adverse health effects such as diabetes, cardiovascular disease, sleep disturbance, depression, and breast cancer. Gastro-esophageal reflux disease (GERD) results in lesions such as reflux esophagitis (RE) and Barrett's esophagus. This study investigated the association between shift work and RE.

Overall and cardiovascular mortality according to 10-year cardiovascular risk of the general health checkup: the Kangbuk Samsung Cohort Study.

Background: According to the occupational accident status analysis in 2020, of 1,180 occupational deaths, 463 were caused by cardiovascular disease (CVD). Workers should be assessed for CVD risk at regular intervals to prevent work-related CVD in accordance with the rules on occupational safety and health standards. However, no previous study has addressed risk and mortality.

Effect of vitamin D deficiency on metabolic syndrome among Korean shift workers.

Objective: This study aimed to investigate the effect of vitamin D deficiency on metabolic syndrome among shift workers.

Methods: This study included 207 756 workers who underwent a comprehensive health examination at a large South Korean university hospital between 2012 and 2018. We performed multivariate-adjusted logistic regression analysis and analyzed mediation and exposure-mediator interaction.

Long working hours and the risk of hypothyroidism in healthy Korean workers: a cohort study.

Objectives: Long working hours have been reported to cause various health problems, but are currently practiced in many countries. Building upon a previous cross-sectional study, the authors aimed to elucidate the causal relationship between long working hours and hypothyroidism through a longitudinal study.

Methods: Data were collected at baseline from 45,259 participants without thyroid disease and with consistent weekly working hours (36-40, 41-52, 53-60, and >60 hours) during the follow-up period.

Long Working Hours and the Risk of Glucose Intolerance: A Cohort Study.

Long working hours have negative effects on the health of workers. Several studies have reported the association between long working hours and both diabetes and prediabetes. Therefore, we aimed to examine the temporal relationship between long working hours and glucose intolerance.

Association between sitting-time at work and incidence of erosive esophagitis diagnosed by esophagogastroduodenoscopy: a Korean cohort study.

Background: Most previous longitudinal studies on lifestyle and gastroesophageal reflux disease (GERD) have focused on physical activity rather than sitting time. The main purpose of this study was to investigate the relationship between prolonged sitting time and the development of erosive esophagitis (EE).

Methods: A self-report questionnaire was used for measuring sitting time in the Kangbuk Samsung Health Study.

Association Between Working Hours and Poor Glycemic Control in Patients With Diabetes: The Kangbuk Samsung Health Study.

Objective: This study aimed to evaluate the relationship between working hours and glycemic control.

Methods: Study was performed among Korean participants who underwent at least two health screening examinations between 2012 and 2018. The study included 2169 participants who were older than 40 years and undergoing treatment for diabetes at baseline.

The effect of long working hours on developing type 2 diabetes in adults with prediabetes: The Kangbuk Samsung Cohort Study.

Background: Long working hours are known to account for approximately one-third of the total expected work-related diseases, and much interest and research on long working hours have recently been conducted. Additionally, as the prevalence of prediabetes and the high-risk group for diabetes are increasing worldwide, interest in prediabetes is also rising. However, few studies have addressed the development of type 2 diabetes and long working hours in prediabetes.

The association between prolonged sedentary time and coronary artery calcification in young healthy men in Korea: a cohort study.

Coronary artery calcium score (CACS) is a useful method for predicting coronary artery disease in asymptomatic adults. In this study, we investigated the association between prolonged sedentary time and CACS. A cohort study was conducted in 14949 men with negative CACS (CACS = 0) at baseline who were followed up at least once.

Working Hours and Depressive and Anxiety Symptoms According to Shift Work and Gender.

Objectives: We aimed to analyze the relationship between long working hours and depressive and anxiety symptoms according to gender and shift work.

Methods: After dividing shift and day workers according to sex, multiple logistic regression analysis was performed to investigate the relationship between weekly working hours and both depressive and anxiety symptoms.

Results: Both depressive and anxiety symptoms were significantly higher in weekly working 40 to 52 and more than 52 hours compared with working fewer than 40 hours in female day workers.

Erratum: Need for individual-based evaluation to determine the association between humidifier disinfectants and health injuries.

[This corrects the article e21 in vol. 33.].

Need for individual-based evaluation to determine the association between humidifier disinfectants and health injuries.

Background: Injuries caused by humidifier disinfectants (HDs) can no longer be grouped under the concept of HD lung injury. Focusing on individual cases, we were able to evaluate the relevance not only of diseases for which epidemiological correlation is recognized but also all diseases and symptoms that the victims complain of.

Methods: In-depth interviews and reassessment of 113 HD-exposed patients who had not been acknowledged as victims by the government were conducted, and their medical records were reviewed.

Cross-sectional association between long working hours and endoscopic gastritis: the Kangbuk Samsung Health Study.

Objectives: This study aimed to determine the cross-sectional association between long working hours and gastritis diagnosed by endoscopy.

Design: Cross-sectional study.

Setting: Large university hospitals in Seoul and Suwon, South Korea.

A longitudinal study of working hours and chronic kidney disease in healthy workers: The Kangbuk Samsung Health Study.

Objectives: Long working hours are linked to an increased risk of exposure to work safety hazards that threaten the health of workers. To date, only a few cross-sectional studies regarding the relationship between working characteristics, such as over-workload and chronic kidney disease (CKD) have been reported. Therefore, in this longitudinal study, we aimed to examine the direct relationship between long working hours and the incidence of CKD.

Association of Long Working Hours With Marital Status Changes in South Korea: A Cohort Study.

Objective: This study investigated the relationship between long working hours and the incidence of divorce or separation among Korean female and male workers.

Methods: A cohort study was conducted in 125,108 Korean workers, married at baseline, who attended health examinations between 2012 and 2017 and had been followed annually or biennially until December 31, 2018. The weekly working hours and marital status changes were measured using self-administered questionnaires.

A Longitudinal Study of the Relationship between Shift Work and Prostate-Specific Antigen in Healthy Male Workers.

As shift work has become prevalent globally, it is important to evaluate the health effects of shift work on employees. Several studies have demonstrated a positive association between shift work and prostate cancer. Therefore, we aimed to further examine the relationship between shift work and elevated prostate-specific antigen (PSA).

Long working hours are associated with a higher risk of non-alcoholic fatty liver disease: A large population-based Korean cohort study.

Background: Non-alcoholic fatty liver disease (NAFLD), a common chronic liver disease, may progress to fibrosis, cirrhosis, hepatocellular carcinoma, and liver failure. But only a few cross-sectional studies have reported an association of NAFLD with working hours. This cohort study further examined the association between working hours and the development of NAFLD.

Association between Shift Work and Reflux Esophagitis: The Kangbuk Samsung Health Study.

This cross-sectional study investigated the relationship between shift work and reflux esophagitis verified by endoscopic findings. Participants underwent a comprehensive health examination and esophagogastroduodenoscopy between January 2011 and December 2018. We examined endoscopic findings and performed multivariate-adjusted regression analysis of the association between shift work and reflux esophagitis using multiple demographic and clinical factors.

Cross-sectional association between long working hours and liver function: the Kangbuk Samsung Health Study.

Objectives: Although the effects of long working hours on liver function remain unclear, in South Korea, there is a social perception that long working hours are associated with poor liver function. Thus, long working hours have recently become a major issue. This study aimed to determine the association between long working hours and liver function, as indicated by the alanine transaminase (ALT) levels.