Moderate obstructive sleep apnea and cardiovascular outcomes in older adults: a propensity score-matched multicenter study (CPAGE-MODE study).

Study Objectives: Obstructive sleep apnea (OSA) has been associated with cardiovascular events (CVEs), although recent randomized controlled trials have not demonstrated that long-term continuous positive airway pressure (CPAP) prevents CVEs. Our objective was to determine the effect of CPAP on older adults with moderate OSA regarding CVE reduction.

Methods: An observational and multicenter study of a cohort of older adults (> 70 years of age) diagnosed with moderate OSA (apnea-hypopnea index 15.

Projected hydrologic changes over the north of the Iberian Peninsula using a Euro-CORDEX multi-model ensemble.

This study explores the impacts of climate change on the hydrology of the headwater areas of the Duero River Basin, the largest basin of the Iberian Peninsula. To this end, an ensemble of 18 Euro-CORDEX model experiments was gathered for two periods, 1975-2005 and 2021-2100, under two Representative Concentration Pathways (RCP4.5 and RCP8.

Projected changes in the Iberian Peninsula drought characteristics.

High spatial resolution drought projections for the Iberian Peninsula (IP) have been examined in terms of duration, frequency, and severity of drought events. For this end, a set of regional climate simulations was completed using the Weather Research and Forecasting (WRF) model driven by two global climate models (GCMs), the CCSM4 and the MPI-ESM-LR, for a near (2021-2050) and a far (2071-2100) future, and under two representative concentration pathway (RCP) scenarios (RCP4.5 and RCP8.

Immunotoxicity of polystyrene nanoplastics in different hemocyte subpopulations of Mytilus galloprovincialis.

Plastic represents 60-80% of litter in the ocean. Degradation of plastic to small fragments leads to the formation of microplastics (MPs <5 mm) and nanoplastics (NPs <1 µm). One of the most widely used and representative plastics found in the ocean is polystyrene (PS).

Future changes in land and atmospheric variables: An analysis of their couplings in the Iberian Peninsula.

This work investigates climate-change projections over a transitional region between dry and wet climates, the Iberian Peninsula (IP). With this purpose, the Weather Research and Forecasting (WRF) model, driven by two global climate models (CCSM4 and MPI-ESM-LR) previously bias-corrected, was used to generate high-resolution climate information. Simulations were carried out for two periods, 1980-2014 and 2071-2100, and under two representative concentration pathways (RCP4.

CeO NPs, toxic or protective to phytoplankton? Charge of nanoparticles and cell wall as factors which cause changes in cell complexity.

CeO nanoparticles (CeO NPs) are well-known for their catalytic properties and antioxidant potential. Recent uses in therapy are based on the Ce ions released by CeO NPs. Reactions involving redox cycles between Ce and Ce oxidation stage seem to promote scavenging of reactive oxygen species (ROS), thus protecting cells from oxygen damage.