Contributions of Gene Modules Regulated by Essential Noncoding RNA in Colon Adenocarcinoma Progression.

Noncoding RNAs (ncRNAs), especially microRNA (miRNA) and long noncoding RNA (lncRNA), have an impact on a variety of important biological processes during colon adenocarcinoma (COAD) progression. This includes chromatin organization, transcriptional and posttranscriptional regulation, and cell-cell signaling. The aim of this study is to identify the ncRNA-regulated modules that accompany the progression of COAD and to analyze their mechanisms, in order to screen the potential prognostic biomarkers for COAD.

[Extraction, combination and distribution regularity of syndrome elements in patients with variant angina pectoris].

Objective: To explore the pathogenesis characteristics of variant angina pectoris (VAP) by extracting its syndrome elements and analyzing the combination and distribution regularity of the syndrome elements.

Methods: One hundred and seventy-five case files of VAP patients were collected. The extraction of syndrome elements and symptom contribution to syndrome was completed by the partition method of complex system based on entropy theory.

[Application of entropy-based complex systems partition method in research on quantizing TCM syndrome diagnostic criteria of angina pectoris].

Objective: To establish the quantized criteria for TCM syndrome diagnosis of angina pectoris (AP) using the entropy-based complex systems partition method (EBCSPM).

Methods: Four hundred and three AP patients were randomly assigned to two groups: the operation group (302 cases) and the examination group (101 cases). The symptomatic information of the patients was extracted using EBCSPM to make sure the contribution degree of each symptom to syndrome diagnosis, and the diagnostic threshold was established by the analysis of receiver operating characteristic curves (ROC).