acts as a pathobiont promoting the biofilm virulence and cariogenicity of in adult severe caries.

Adult severe caries (ASC) brings severe oral dysfunction and treatment difficulties to patients, and yet no clear pathogenic mechanism for it has been found. This study is focused on the composition of dental plaque microbiome profiles in order to identify disease-relevant species and to investigate into their interactions with the . Samples of dental plaque were collected for metagenomic analysis.