Potential of Forsythoside I as a therapeutic approach for acute lung injury: Involvement of TXNIP/NLRP3 inflammasome.

Objective: To explore the role of Forsythoside I (FI) in acute lung injury (ALI) mouse and its underling mechanism.

Methods: The cell models of ALI are constructed by LPS induction. After pretreatment with different concentrations of FI, the lung injury is assessed by pathological changes of lung tissues and cell apoptosis.