Clinical Efficacy and Safety of Endoscopic Treatment of Gastrointestinal Stromal Tumors in the Stomach.

Background/aims: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors in the stomach. We evaluated the clinical outcomes of endoscopic treatment for gastric GISTs.

Methods: This is a single center, retrospective study that enrolled 135 cases of gastric subepithelial tumors (SETs) resected by endoscopic procedures and confirmed as GISTs by histopathology from March 2005 to July 2019.

Processing of ferromanganese fumes into high-purity manganese sulphate monohydrate.

A novel process for recovering manganese (Mn) values from two types of ferromanganese (FeMn) fumes (wastes from smelters) was developed incorporating several stages of leaching, roasting, and precipitation. Fumes containing high K (as KO) were first leached in water at ambient conditions to recover K, purified to remove metal impurities, and precipitated as 99.9% pure KSO.

Structural Characteristics of a Conical-Frustum-Patterned Stretchable Heater in an External-Force Environment.

Stretchable heaters are mechanically and biomedically advantageous because they are more flexible than the conventional microheaters. To determine the way that a heater can be used appropriately in a wide range of application fields, studies on the mechanical and thermal characteristics regarding various film configurations are underway. In this study, the mechanical characteristics of conical-frustum-patterned stretchable heaters with various configurations with upper-radius (R1), bottom-radius (R2), and height (h) aspect ratios were numerically investigated when tensile forces and bending moments were applied to the film of heater.

Association of Plasminogen Activator Inhibitor-1 (PAI-1) Gene Polymorphisms with Osteoporotic Vertebral Compression Fractures (OVCFs) in Postmenopausal Women.

Osteoporosis and osteoporotic fractures are strongly associated with mortality and morbidity, both in developing and developed countries. Menopause accelerates bone loss due to estrogen deficiency and age-related linear bone loss. We investigated plasminogen activator inhibitor-1 () gene polymorphisms in postmenopausal women with osteoporotic vertebral compression fractures (OVCFs).

[Inverted Hyperplastic Polyp in Stomach: A Case Report and Literature Review].

An inverted hyperplastic polyp (IHP) found in stomach is rare and characterized by downward growth of hyperplastic mucosal component into the submucosa. Because of such characteristic, IHP can be misdiagnosed as subepithelial tumor or malignant tumor. In fact, adenocarcinoma was reported to have coexisted with gastric IHP in several previous reports.

Effects of CH4893237, a new orally active estrogen receptor downregulator, on breast cancer xenograft models with low serum estrogen levels.

We compared the antitumor efficacy and estrogen receptor (ER) degradation of CH4893237, a new orally active selective ER downregulator, with fulvestrant and tamoxifen in human breast cancer xenografts with low levels of serum estrogen (E2) (50.6, 22.9 and <16.

Erythroid cell-specific alpha-globin gene regulation by the CP2 transcription factor family.

We previously demonstrated that ubiquitously expressed CP2c exerts potent erythroid-specific transactivation of alpha-globin through an unknown mechanism. This mechanism is reported here to involve specific CP2 splice variants and protein inhibitor of activated STAT1 (PIAS1). We identify a novel murine splice isoform of CP2, CP2b, which is identical to CP2a except that it has an additional 36 amino acids encoded by an extra exon.