Increase in breast cancer incidence among older women in Mumbai: 30-year trends and predictions to 2025.

Background: Increasing trends in the incidence of breast cancer have been observed in India, including Mumbai. These have likely stemmed from an increasing adoption of lifestyle factors more akin to those commonly observed in westernized countries. Analyses of breast cancer trends and corresponding estimation of the future burden are necessary to better plan rationale cancer control programmes within the country.

Changing trends of chronic myeloid leukemia in greater Mumbai, India over a period of 30 years.

Background: Little is known about burden of chronic myeloid leukemia (CML) in India. There is a recent interest to observe incidence and mortality because of advent of new diagnostic and treatment policies for CML.

Materials And Methods: We extracted data from the oldest population-based cancer registry of Mumbai for 30 years period from 1976-2005 to observe incidence and mortality rates of CML.

Fine aerosol and PAH carcinogenicity estimation in outdoor environment of Mumbai City, India.

Exposure to fine particles has been shown to cause severe human health impacts. In the present study, outdoor fine particles as well as elemental and organic carbon concentrations were measured in four locations within Mumbai city, India, during 2007-2008. The average outdoor PM(2.

Trends in breast, ovarian and cervical cancer incidence in Mumbai, India over a 30-year period, 1976-2005: an age-period-cohort analysis.

Background: Demographic, socioeconomic and cultural changes in India have increased longevity, delayed childbearing, decreased parity and resulted in a more westernised lifestyle, contributing to the increasing burden of cancer, especially among women.

Methods: We evaluated secular changes in the incidence of breast, cervical and ovarian cancer in Mumbai women aged 30-64 between 1976 and 2005. Age-standardised incidence rates were calculated and presented by site and calendar period.

Epidemiological review of gastric cancer in India.

Stomach cancer is the one of the leading cause of cancer in southern region of India. Its incidence is decreasing worldwide yet on global scale stomach cancer remains one of the most common causes of cancer death. Etiology of gastric cancer includes Helicobacter pylori infection, diet and lifestyle, tobacco, alcohol and genetic susceptibility.

Cancer survival in Mumbai (Bombay), India, 1992-1999.

The Bombay cancer registry is the second oldest population-based cancer registry in Asia, and the first of its kind in India. It was established in 1963, and registration of cases is done by active methods. Data on survival from 28 cancer sites or types registered during 1992-1999 are reported.

Association of tobacco habits, including bidi smoking, with overall and site-specific cancer incidence: results from the Mumbai cohort study.

Objective: Bidis are hand-rolled cigarettes commonly smoked in South Asia and are marketed to Western populations as a safer alternative to conventional cigarettes. This study examined the association between bidis and other forms of tobacco use and cancer incidence in an urban developing country population.

Methods: Using data from the large, well-characterized Mumbai cohort study, adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) were computed from Cox proportional hazards regression models in order to compare the relative effect of various forms of tobacco use on cancer incidence.

Cancer epidemiology in South Asia - past, present and future.

Pakistan, India, Sri Lanka, Bangladesh, Nepal and Bhutan, with their total population of more than 1,500 million, make up the subcontinent of South Asia. Despite massive diversity across the region, there are sufficient similarities to warrant a collective approach to chronic disease control, including development of cancer control programs. Cancer is already a major problem and there are general similarities in the prevalence patterns.

Cancer survival in Africa, Asia, and Central America: a population-based study.

Background: Population-based cancer survival data, a key indicator for monitoring progress against cancer, are not widely available from countries in Africa, Asia, and Central America. The aim of this study is to describe and discuss cancer survival in these regions.

Methods: Survival analysis was done for 341 658 patients diagnosed with various cancers from 1990 to 2001 and followed up to 2003, from 25 population-based cancer registries in 12 countries in sub-Saharan Africa (The Gambia, Uganda), Central America (Costa Rica), and Asia (China, India, Pakistan, Philippines, Saudi Arabia, Singapore, South Korea, Thailand, Turkey).

Lifetime risk and trends in lung cancer incidence in greater Mumbai.

Objective: To estimate the probability of developing lung cancer in the entire life span of the people of Greater Mumbai and variation according to age and sex. Information on cancer incidence trends in a community forms the scientific basis for planning and organising prevention, diagnosis and treatment. During the last 24 year period, a total of 11,458 lung cancer cases were registered (9,052 male and 2,406 female) by the Bombay Cancer Registry.

Trends in the incidence of Non-Hodgkin's lymphoma in India.

Non-Hodgkin's lymphoma is the 11th most common cancer in terms of incidence. It is most frequent in high income countries, with rates more than twice those of middle--to low-income countries. It is usually fatal, with a 5 year survival rate of less than 35 percent.

Geriatric cancers in India: an epidemiological and demographic overview.

This article provides an overview of aspects of the burden of cancer in the elderly, in India highlighting certain demographic and epidemiological data. In India the normal retirement age is 60 years, so the definition of the elderly, in India is considered above the age of 60 years. Information on the aging of the Indian population is based on various census figures, cancer incidence figures are taken from Mumbai registry data.

Trends in the brain cancer incidence in India.

Trends in cancers of the central nervous system in both sexes in five Indian population based cancer registries (Mumbai, Chennai, Bangalore, Delhi & Bhopal) were evaluated over a period of the last two decades. For this purpose we applied a model that fits the data is the logarithm of Y=ABx which represents a Linear Regression model. This approach revealed an increasing trend in cancers of nervous system in both sexes throughout the entire period of observation in almost all registries.

Trends in the prostate cancer incidence in India.

Trends in prostate cancer in five population-based cancer Registries (Mumbai, Chennai, Bangalore, Delhi & Bhopal) in India were studied over a period of two decades using a model that fitting the data as the logarithm of Y=ABx which represents a Linear Regression model. This approach showed increasing trends in the age adjusted incidence rates throughout the entire period of observation for most of the registries, especially in Chennai and Bhopal and to the least extent in Mumbai. Particularly in Asia we face a future major increase in the rates of prostate cancer.

Trends in cancer incidence in female breast, cervix uteri, corpus uteri, and ovary in India.

Trends in breast, cervix uteri, corpus uteri and ovarian cancers in six population based cancer registries (Mumbai, Bangalore, Chennai, Delhi, Bhopal, and Barshi) were evaluated over a period of the last two decades. For studying trends we used a model that fits this data is the logarithm of Y=ABx which represents a Linear Regression model. This approach showed a decreasing trend for cancer of the cervix and increasing trends for cancers of breast, ovary and corpus uteri throughout the entire period of observation in most of the registries.

Trends in cancer incidence in esophagus, stomach, colon, rectum and liver in males in India.

Time trends in cancers of the esophagus, stomach, colon, rectum and liver cancers among the male population in five Indian urban population based cancer registries (Mumbai, Bangalore, Chennai, Delhi, and Bhopal) were examined over the period of the last two decades. The model applied fits data to the logarithm of Y=ABx. This Linear Regression method showed decreasing trends in age-adjusted incidence rates for cancers of the stomach and esophagus, especially in Bjopal, and increasing trends for colon and rectum and liver, throughout the entire period of observation in most of the registries.

Trends in incidence of head and neck cancers in India.

Information relating to cancer incidence trends forms the scientific basis for the planning and organization of prevention, diagnosis and treatment of cancer in a community. An attempt was here made to study the trends in the age adjusted incidence rates for the sites of head and neck cancers in Mumbai, Bangalore, Chennai, Delhi, Bhopal, and Barshi registry's populations. For carrying out trend analysis the gum, the floor of mouth, the mucosa of cheek, the hard and soft palate and the uvula were grouped together and assigned as cancers of mouth.

Cancer incidence in Indians from three areas: Delhi and Mumbai, India, and British Columbia, Canada.

Background: Studies of immigrants have provided unique opportunities for examining disparities in cancer screening and the impact of lifestyles and environmental exposures on cancer risk. Findings have been useful for planning cancer control strategies and generating etiological hypotheses. Although India is a leading source of immigration to British Columbia (BC), Canada, little is known about the cancer profiles of Indo-Canadians, information needed for planning health services and health promotion initiatives for this population.

Role of the cancer registries in determining cancer mortality in Asia?

Data on incidence, prevalence, and disease specific mortality are frequently incomplete, not very reliable or are lacking in many countries particularly in Asia and Africa. In the absence of dependable data from the Civil Registration System (CRS), many countries have developed their own Sample Registration System (SRS). Due to several socio-economic constraints cause is not adequately noted in the death certificates.

Geographic variation in cancer incidence and its patterns in urban Maharashtra, 2001.

In this paper an attempt has been made to study the geographic variations in cancer incidence and its pattern in Urban Maharashtra. Data collected by Mumbai, Poona, Nagpur, and Aurangabad, Population based Cancer Registries, for the year 2001 have been utilized. The incidence patterns by sex, age, and religion has been compared between these four agglomerations.

Social inequalities in cancer with special reference to South Asian countries.

There are major differences in cancer burden across socioeconomic classes, as is evident from the data for cancer incidence and mortality from Greater Mumbai, India. Changes over time are also evident and recently there has been a clear shift to increasing breast cancer particularly in well-educated women, who conversely are at much lower risk of cervical cancer. With infection-related and tobacco-related cancers, programs of prevention and early detection will yield desirable results only if it is associated with a program directed towards elimination of poverty, illiteracy and restoring social inequality.

Respiratory cancer population-based survival in Mumbai, India.

Survival experience of patients with cancer of the larynx (ICD-32) or lung (ICD-34) registered by the Mumbai (Bombay) population based cancer registry, India, during the years 1992-94 was determined. The vital statistics of the patients were established by matching with death certificates from the Mumbai Municipal death register and by active methods such as telephone enquiry, reply-paid postal enquiry, house visits and scrutiny of case records. Of the 1905 (675 larynx and 1230 lung) eligible cases for analysis, 1480 were dead (450 larynx and 1030 lung) and 425 were alive (225 larynx and 200 lung).

Assessing cancer burden in rural India: an analysis by cause of death statistics.

India lacks nationwide cancer registration and systematic death registration. Gaining insight into the magnitude of the cancer problem in India depends mainly on 14 population based cancer registries, which provide relatively accurate statistics although the area and population cover by these registries is minimal at about 7% (20% Urban and 1 % Rural). With estimation of cancer burden from other sources, paucity of adequate data on the one hand and the complex pathogenesis of disease on other makes for complexity in dealing with rural populations.

Cumulative risk and trends in prostate cancer incidence in Mumbai, India.

Background: Information relating to cancer incidence trends in a community forms the scientific basis for the planning and organization of prevention, diagnosis and treatment of cancer. We here estimated the cumulative risk and trends in incidence of prostate cancer in Mumbai, India, using data collected by the Bombay Population-based Cancer Registry from the year 1986 to 2000.

Methods: During the 15 year period, a total of 2864 prostate cancer cases (4.

Population-based survival from cancers of breast, cervix and ovary in women in Mumbai, India.

Background: Breast, cervix and ovarian cancers contribute more than 45% of the total in women in Mumbai and survival proportions for these neoplasms are very high in most developed populations in the World. The authors here report and discuss the population-based survival for these cancers in Mumbai, India.

Methods: Follow-up information on 4865 cancers of breast, cervix and ovary, registered in the Mumbai Population Based Cancer Registry for the period 1992-1994 was obtained by a variety of methods, including matching with death certificates from the Mumbai vital statistics registration system, postal/telephone enquiries, home visits and scrutiny of medical records.