Research into the intervention effect of folic acid on arsenic-induced heart abnormalities in fetal rats during the periconception period.

Background: The incidence of CHD is the highest among birth defects and is increasing year to year. CHD seriously harms the health of infants and young children and presents a large economic burden to families and society. The pathogenesis of CHD and preventive measures are the focus of current research.

The draft genome sequence of forest musk deer (Moschus berezovskii).

Background: The forest musk deer, Moschus berezovskii, is one of seven musk deer (Moschus spp.) and is distributed in Southwest China. Akin to other musk deer, the forest musk deer has been traditionally and is currently hunted for its musk (i.

Risk factors of liver metastasis from advanced pancreatic adenocarcinoma: a large multicenter cohort study.

Background: Clinical prognostic parameters of liver metastasis from pancreatic adenocarcinoma have not been specifically identified.This study is to explore the risk factors of liver metastasis in advanced pancreatic adenocarcinoma (PDAC) patients in China.

Methods: A multicenter cohort study was conducted to explore whether liver metastasis in locally advanced and metastatic PDAC could be reflected by some common laboratory indexes.

Decreased Expression of Aquaporin-1 in Lung Tissue of Silicotic Rats.

Background: Aquaporin-1 (AQP-1), found in the early 1990s, a water channel protein in the cell membranes of mammals, has been reported to play an important role in water balance of the respiratory system. However, there are a few studies about the role of AQP in occupational pulmonary disease such as silicosis. This study is to explore the information of aquaporin-1 (AQP-1) in the pathogenesis of silicosis by examining AQP expression, distribution, and location in the lung tissue of a silicotic rat model.

Observation of η'→π+ π π+ π- and η'→π+π- π0 π0.

Using a sample of 1.3 × 10(9)  J/ψ events collected with the BESIII detector, we report the first observation of η(')→π(+)π(-)π(+)π(-) and η(')→π(+)π(-)π(0)π(0). The measured branching fractions are B(η(')→π(+)π(-)π(+)π(-)) = [8.

Matrix metalloproteinase-dependent turnover of cartilage, synovial membrane, and connective tissue is elevated in rats with collagen induced arthritis.

Background: Rheumatoid arthritis is a disease affecting the extracellular matrix of especially synovial joints. The thickness of the synovial membrane increases and surrounding tissue degrades, leading to altered collagen balance in the tissues. In this study, we investigated the altered tissue balance of cartilage, synovial membrane, and connective tissue in collagen induced arthritis (CIA) in rats.

Novel role of platelets in mediating inflammatory responses and ventricular rupture or remodeling following myocardial infarction.

Objective: The goal of this study was to investigate the role of platelets in systemic and cardiac inflammatory responses and the development of postinfarct ventricular complications, as well as the efficacy of antiplatelet interventions.

Methods And Results: Using a mouse myocardial infarction (MI) model, we determined platelet accumulation and severity of inflammation within the infarcted myocardium by immunohistochemistry and biochemical assays, analyzed peripheral blood platelet-leukocyte conjugation using flow cytometry, and tested antiplatelet interventions, including thienopyridines and platelet depletion. Platelets accumulated within the infarcted region early post-MI and colocalized with inflammatory cells.

Quiet Zone Within a Seismic Gap near Western Nicaragua: Possible Location of a Future Large Earthquake.

A 5700-square-kilometer quiet zone occurs in the midst of the locations of more than 4000 earthquakes off the Pacific coast of Nicaragua. The region is indicated by the seismic gap technique to be a likely location for an earthquake of magnitude larger than 7. The quiet zone has existed since at least 1950; the last large earthquake originating from this area occurred in 1898 and was of magnitude 7.