Synopsis of recent research by authors named "Yener Koc"
- Yener Koc's recent research focuses primarily on optimizing hematopoietic stem cell transplantation (HSCT) methods, particularly for acute myeloid leukemia (AML) and other malignancies, by comparing various graft-versus-host disease (GVHD) prophylaxis strategies, including post-transplantation cyclophosphamide (PTCy) and calcineurin inhibitors.
- A significant finding from his studies indicates that age and donor type play crucial roles in transplantation outcomes, revealing that young haploidentical donors may provide better results compared to older mismatched unrelated donors in AML patients in first remission.
- Koc's research also highlights the impact of HLA disparity on transplantation success and the effectiveness of different GVHD prophylaxis regimens, suggesting that careful donor selection and prophylaxis strategy can enhance patient survival rates post-transplant.
