Publications by authors named "Yen-Ping Ho"
Article Synopsis
- Epithelial ovarian cancer (EOC) often becomes resistant to chemotherapy, particularly with the drug paclitaxel, and the role of androgen receptors (AR) in this resistance is not fully understood.
- Research involving various assays revealed that AR directly regulates the expression of ABCG2, which influences how responsive EOC cells are to paclitaxel treatment.
- Using an AR degradation enhancer, ASC-J9, showed promise in overcoming drug resistance in AR-positive EOC tumors, indicating that targeting AR could be an effective strategy for treatment.
Background: The role of midluteal phase gonadotropin-releasing hormone (GnRH) agonist had been an issue of debate. The aim of this retrospective study was to evaluate the effect of a mid-luteal phase GnRH agonist as an additional luteal phase support (LPS) in patients receiving intracytoplasmic sperm injection (ICSI). Additionally, we elucidate which subgroup would gain the most benefit from GnRH agonist as LPS.
View Article and Find Full Text PDFObjective: To investigate the expression of transforming growth interacting factor (TGIF), a Smad transcriptional corepressor, in leiomyoma and matched myometrial tissue samples and the effect of TGIF overexpression in myometrial cells.
Design: Experimental study.
Setting: Tertiary university hospital.