Publications by authors named "Yen-Ling Shen"
Article Synopsis
- Researchers studied how nickel oxide nanoparticles (NiONPs) affect lung inflammation and injury by administering them to mice and evaluating the effects over 28 days.
- Key findings included significant increases in harmful markers like LDH and IL-6, along with evidence of airway inflammation that varied by dose and duration.
- Over time, damage included lung fibrosis and changes in important biochemical pathways, indicating a clear link between NiONP exposure and lung inflammation.
Recent studies suggest that exposure to air pollution might be associated with severity of sleep-disordered breathing (SDB). However, the association between air pollution exposure, especially particulate matter with aerodynamic diameters <= 2.5 μm (PM), and SDB is still unclear.
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- * The study utilized a combination of imaging techniques and cell culture experiments to reveal that ZnONPs caused regional lung inflammation, particularly increasing the p63 tumor marker and altering other cellular markers related to lung health.
- * Findings indicate that exposure to ZnONPs may pose risks to lung health, highlighting the need for further research into their pulmonary toxicity and the biological mechanisms involved.