Background: Imperatorin is a naturally occurring furocoumarin derivative found in traditional Chinese medicine Angelica dahurica for its anticancer, antihypertensive, and antidiabetic properties. Chronic kidney disease (CKD) is a global health issue, characterized by a high prevalence, significant morbidity and mortality, and a range of related complications.
Objective: This study aims to investigate the protective effects of imperatorin treatment and the specific underlying mechanisms in progressive CKD.
There is a consistent demand for developing highly sensitive, stable, cost-effective, and easy-to-fabricate creatinine sensors as creatinine is a reliable indicator of kidney and muscle-related disorders. Herein, we reported a highly sensitive and selective non-enzymatic electrochemical creatinine sensor via modifying poly(3,4 ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) coated indium tin oxide (ITO) substrate by zeolitic imidazolate framework-8 nanoparticles (ZIF-8 NPs). The topography, crystallinity, and composition of the sensing electrode were characterized by field emission scanning electron microscopy (FESEM), atomic force microscopy (AFM), X-ray diffraction (XRD), and X-ray photoelectron spectroscopy (XPS).
View Article and Find Full Text PDFThe effect of surface plasmon resonance (SPR) on the blinking emission of photoluminescence from noble metal nanostructures still requires further investigation in quantum mechanics and limits their applications. We investigate one photon luminescent emission intermittency of noble metal nanostructures with differently sized sea-urchin-shaped nanoparticles, known as nano-sea-urchins (NSUs). The probability of the "on" process in one photon luminescent emission intermittency of NSUs increases due to the strong electric field of SPR.
View Article and Find Full Text PDFFew ellipsometric studies have been conducted on Au self-assembled monolayers (SAM), with large discrepancies obtained for refractive index values. Because the Au NPs layer is a kind of composite layer, Au NPs and void, the effective media approximate (EMA) model was employed to investigate the optical properties of Au NPs. The reflective coefficient (approximately 1.
View Article and Find Full Text PDFNatural pigment can act as an inexpensive and biologically-friendly dye, which is fabricated on a TiO2/FTO substrate. Natural pigments promote the efficiency of the photoelectric conversion in water-based DSSC with the aqueous electrolyte of the Ce+4/+3 system. The open-circuit voltage (Voc) of natural pigment in water-based DSSC is 0.
View Article and Find Full Text PDFWe prepared gold nanoparticles (Au NPs) by only using trisodium citrate as the stabilizer. The detailed reaction mechanisms of S(N)1 and E1 reactions are examined and evidenced in this study by FTIR data. Citric acid is a kind of tertiary substrate.
View Article and Find Full Text PDFThe ellipsometric measurement of local surface plasmon resonance (LSPR) caused by the adsorption of chitosan on layer-by-layer gold nanoparticles (Au NPs) was investigated. Six nanometer (6 nm) Au NPs were prepared and layer-by-layer Au NPs were fabricated to shift the LSPR to 520, 540, and 560 nm, respectively, due to the Mie theory. The thicknesses and the fractions of the layer-by-layer Au NPs were measured accurately using a combination of the Fresnel equation and the Maxwell-Garnett equations for ellipsometry.
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