Publications by authors named "Yen May Ong"
Article Synopsis
- Astrocytes respond to wounds by extending microtubule-rich processes and polarizing, but β1 integrin null astrocytes fail to do so, indicating the importance of integrins in directional migration.
- Expression of β1 integrin rescues centrosome integrity and allows normal polarization and process extension, showing that integrin activity is crucial for astrocyte function during wounds.
- The study highlights that centrosome integrity, influenced by non-muscle myosin II (NMII) rather than FAK or ILK, is essential for astrocytes' ability to polarize and respond to injury.
