A clinical-laboratory survey of 1952 patients with acute feverish diseases developing after tick bite was carried out in the Pre-Ural region of Russia, which is endemic for tick-borne encephalitis and ixodid tick-borne borreliosis, in 1999-2001. Enzyme-linked immunosorbent assay and indirect immunofluorescence assay were used for the detection of tick-borne encephalitis, ixodid tick-borne borreliosis and ehrlichiosis specific antibodies. Tick-borne encephalitis was diagnosed in 22.
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