Publications by authors named "Yeimy V Ariza"
Article Synopsis
- Pharmacogenomics (PGx) is a growing field in developing countries, particularly in Latin America and the Caribbean (LAC), but research and information are limited, making it challenging to apply findings across diverse populations.
- The study reviewed PGx knowledge among the LAC scientific community, identified barriers to its clinical use, and surveyed 106 professionals to evaluate these obstacles, revealing that the primary barrier is the lack of guidelines for implementing PGx in practice.
- Despite these challenges, LAC has contributed 3.44% of global PGx publications and identified gene/drug pairs, such as tamoxifen and clopidogrel, as significant for improving genomic medicine responses, although cost-effectiveness concerns remain a critical issue.
Purpose: Ubiquitin ligase genes can act as oncogenes or tumor suppressor genes. They play a role in various diseases, including development and progression of breast cancer; the objective of this study was to evaluate the association of common variants in the () gene with breast cancer risk in a sample of Colombian population.
Methods: We carried out a case-control study to investigate associations of variants in with breast cancer in women from Colombia.