Publications by authors named "Yeh-Ching Chung"
Chondrosarcoma is a rare type of cancer that can affect the upper urinary tract. Because of its rarity, the clinical presentation of chondrosarcoma can be similar to other urinary tract conditions, such as renal colic, hematuria, and urothelial carcinoma. The primary treatment for chondrosarcoma is the surgical removal of the tumor, and radiation or chemotherapy may be used for advanced cases.
View Article and Find Full Text PDFFor biological applications, sequence alignment is an important strategy to analyze DNA and protein sequences. Multiple sequence alignment is an essential methodology to study biological data, such as homology modeling, phylogenetic reconstruction and etc. However, multiple sequence alignment is a NP-hard problem.
View Article and Find Full Text PDFArticle Synopsis
- Cardiovascular disease, particularly myocardial infarction (MI), is a leading cause of death in Taiwan, often linked to hyperlipidemia and atherosclerosis.
- This study analyzed copy number variations (CNV) in blood samples from 31 MI patients with hyperlipidemia, identifying seven significant CNV regions associated with these conditions.
- The findings suggest these CNV regions could serve as potential biomarkers for early diagnosis of hyperlipidemia and MI, offering new avenues for research.
Multiple genome sequences alignment algorithm based on coding regions.
Int J Comput Biol Drug Des
September 2011
Article Synopsis
- Multiple Sequence Alignment (MSA) is a key tool in computational biology used to analyze DNA similarities, evolutionary relationships, and common patterns.
- Existing MSA methods are effective for various sequences but haven't focused on coding region sequences, which is where CORAL-M comes in.
- CORAL-M is a new heuristic method that uses a codon-based model for faster alignment of coding regions in multiple genomes, showing superior results by identifying more functional sites compared to other tools.
Background: Identifying the regions associated with protein function is a singularly important task in the post-genomic era. Biological studies often identify functional enzyme residues by amino acid sequences, particularly when related structural information is unavailable. In some cases of protein superfamilies, functional residues are difficult to detect by current alignment tools or evolutionary strategies when phylogenetic relationships do not parallel their protein functions.
View Article and Find Full Text PDFA polygon model for wireless sensor network deployment with directional sensing areas.
Sensors (Basel)
September 2012
The modeling of the sensing area of a sensor node is essential for the deployment algorithm of wireless sensor networks (WSNs). In this paper, a polygon model is proposed for the sensor node with directional sensing area. In addition, a WSN deployment algorithm is presented with topology control and scoring mechanisms to maintain network connectivity and improve sensing coverage rate.
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