Operation mechanism analysis and parameter optimization of airflow-rotating disc separation device for agricultural film fragments.

To reduce the impurity and loss rates during agricultural film fragment separation, an integrated airflow and mechanical separation approach was devised, and the airflow-rotating disc separation device with air suction mechanism and curved disc rotating screening mechanism was designed. The processes of throwing, collision and slipping were analyzed, considering film compressibility. The factors affecting the separation performance were identified as feeding quantity, airflow velocity and disc rotational velocity.

PPARβ/δ Activation Improves Corticosterone-Induced Oxidative Stress Damage in Astrocytes by Targeting UBR5/ATM Signaling.

Oxidative stress-mediated astrocytic damage contributes to nerve injury and the development of depression, especially under stress conditions. Peroxisomes and pexophagy are essential for balancing oxidative stress and protein degradation products. Our previous findings suggest that peroxisome proliferators-activated receptor β/δ (PPARβ/δ) activation significantly alleviates depressive behaviors by preventing astrocytic injury.

PD-1/PD-L1 axis is involved in the interaction between microglial polarization and glioma.

The tumor microenvironment plays a vital role in glioblastoma growth and invasion. PD-1 and PD-L1 modulate the immunity in the brain tumor microenvironment. However, the underlying mechanisms remain unclear.