Synopsis of recent research by authors named "Yeeun Shim"
- Yeeun Shim's research primarily focuses on the application of optical genome mapping (OGM) technologies for molecular diagnosis and understanding of various genetic disorders, including muscular dystrophies and hematologic malignancies, highlighting OGM's superior capabilities over conventional methods in detecting structural variants.
- Recent findings demonstrate the utility of OGM in identifying clinically relevant genomic rearrangements in prostate cancer and successfully investigating the genetic basis of resistance to PARP inhibitors in BRCA-mutated ovarian cancer, suggesting significant implications for personalized treatment strategies.
- Additionally, Shim's studies extend into carbohydrate biochemistry, exploring enzymatic modifications of starches to enhance digestibility, potentially influencing dietary management of glycemic responses, thereby addressing public health concerns related to metabolism and nutrition.