Publications by authors named "Yeeun Kwon"
Effects of Hot Water Extract and Oregonin on Muscle Loss and Muscle Atrophy in C2C12 Murine Skeletal Muscle Cells.
Pharmaceuticals (Basel)
December 2024
Sarcopenia is characterized by the loss of muscle mass and function, increases in mortality rate, and risk of comorbidities in the elderly. This study evaluated the effects of hot water extract (AJHW) and its active compound, oregonin, on muscle atrophy and apoptosis in vitro. AJHW underwent phytochemical analysis.
View Article and Find Full Text PDFArticle Synopsis
- * This study investigates the effects of catechin 7-O--D-apiofuranoside on muscle cell apoptosis and protein/gene expression in a model of muscle atrophy, using techniques like Western blotting and RT-PCR.
- * Results show that catechin extract reduces muscle-degradation proteins (Atrogin-1, MuRF1) while boosting muscle-synthesis proteins (MyoD, Myogenin), hinting at its potential for preventing muscle loss and promoting health through functional foods and medicines.
Article Synopsis
- Aging causes tissue and cellular changes, mainly due to oxidative stress and inflammation, which lead to diseases related to aging.
- The study investigates the anti-inflammatory and antioxidant properties of Korean Hance, a traditional herb, to combat muscle loss and atrophy through various tests and analyses.
- Results show that the extract supports muscle gene expression, reduces inflammation, and enhances antioxidant levels, suggesting its potential for developing new treatments for muscle atrophy.
This study was conducted to examine the anti-hair loss mechanism of the supercritical fluid extraction-residues extract of by the regulation of cytokine production and hormone function in human dermal follicle papilla cells (HDFPCs). To investigate the modulatory effects on HO-induced cytokines, we measured transforming growth factor-beta and insulin-like growth factor 1 secreted from HDFPCs. To investigate the regulatory effects of supercritical extraction-residues extract of on dihydrotestosterone hormone production, cells were co-incubated with high concentrations of testosterone.
View Article and Find Full Text PDFThe risk of the malignant transformation of oral leukoplakia (OLP) is difficult to predict by histopathology. Melanoma-associated antigen-A (MAGE-A) expression is restricted to malignant cells and may be useful for the more accurate estimation of the potential malignant transformation of pre-malignant lesions. The aim of the present study was to investigate whether the expression of MAGE-A can be used to predict the malignant transformation of OLP.
View Article and Find Full Text PDF