Publications by authors named "Yedi Wang"
Article Synopsis
- RNA methylation plays a crucial role in angiogenesis, with significant implications for health when it becomes abnormal.
- The bibliometric analysis utilized data from the Web of Science database from 2000 to 2022, revealing trends and the impact of publications on this topic through tools like CiteSpace and VOSviewer.
- A total of 382 papers were analyzed, showing exponential growth in research, with China leading in publications; cancer emerged as the primary focus, particularly regarding N6-methyladenosine, signaling its potential as a target for future studies on related disorders.
N6-methyladenosine (mA) modification, as the most common modification method in eukaryotes, is widely involved in numerous physiological and pathological processes, such as embryonic development, malignancy, immune regulation, and premature aging. Under pathological conditions of ocular diseases, changes in mA modification and its metabolism can be detected in aqueous and vitreous humor. At the same time, an increasing number of studies showed that mA modification is involved in the normal development of eye structures and the occurrence and progress of many ophthalmic diseases, especially ocular neovascular diseases, such as diabetic retinopathy, age-related macular degeneration, and melanoma.
View Article and Find Full Text PDFBackground: Gene therapy is a treatment approach at the genetic level, which brings great advances in many diseases and develops rapidly in recent years. Currently, its mechanism of action is mainly through the replacement of missing or defective genes, or the reduction of harmful gene products. However, the application of gene therapy in ophthalmology remains limited.
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