Anti-Aging and Anti-Inflammatory Effects of Compounds from Fresh Roots: A Study on TNF-α/IFN-γ-Induced Skin Cell Damage.

(Korean ginseng) is renowned for its health-promoting properties, attributed to its bioactive compounds, including saponins, polyphenols, and polysaccharides, which possess both antioxidant and anti-aging activities. This study investigated the anti-aging and anti-inflammatory effects of compounds isolated from the hot water extract of fresh roots, evaluating their resistance to TNF-α/IFN-γ-induced skin cell damage. Among 14 compounds, ginsenoside Rf (compound ) showed significant multi-target effects.