Independent Control Over the H/OH Adsorption: Breaking the Trade-Off Between H/OH-Adsorption and HO-Dissociation of Platinum-Group Metal Electrocatalyst for Hydrogen Evolution Reaction.

Platinum-group metals catalysts (such as Rh, Pd, Ir, Pt) have been the most efficient hydrogen evolution reaction (HER) electrocatalysts due to their moderate H adsorption strength, while the high HO-dissociation barrier in alkaline media restrains the catalytic performance of PGM catalysts. However, the optimization of the HO-dissociation barrier and *H/*OH binding energy toward their individual optima is limited due to the constraints of their scaling relationship on a single active site. Here, a coordinatively unsaturated "M─O─W" (M = Rh, Pd, Ir, Pt) active area is constructed, where H and OH species are anchored on Pt-group metal sites and inactive W sites for individual regulation.

Neuroimaging analysis reveals distinct cerebral perfusion responses to fasting-postprandial metabolic switching in Alzheimer's disease patients.

Aims: Extended fasting-postprandial switch intermitting time has been shown to affect Alzheimer's disease (AD). Few studies have investigated the cerebral perfusion response to fasting-postprandial metabolic switching (FMS) in AD patients. We aimed to evaluate the cerebral perfusion response to FMS in AD patients.

Coordination Desymmetrization of Copper Single-Atom Catalyst for Efficient Nitrate Reduction.

Coordination engineering strategy for optimizing the catalytic performance of single-atom catalysts (SACs) has been rapidly developed over the last decade. However, previous reports on copper SACs for nitrate reduction reactions (NORR) have mostly focused on symmetric coordination configurations such as Cu-N and Cu-N. In addition, the mechanism in terms of the regulation of coordination environment and catalytic properties of SACs has not been well demonstrated.

Effects of the Fasting-Postprandial State on Arterial Spin Labeling MRI-Based Cerebral Perfusion Quantification in Alzheimer's Disease.

Background: The fasting-postprandial state remains an underrecognized confounding factor for quantifying cerebral blood flow (CBF) in the cognitive assessment and differential diagnosis of Alzheimer's disease (AD).

Purpose: To investigate the effects of fasting-postprandial state on arterial spin labeling (ASL)-based CBF in AD patients.

Study Type: Prospective.

Unraveling Ros Conversion Through Enhanced Enzyme-Like Activity with Copper-Doped Cerium Oxide for Tumor Nanocatalytic Therapy.

Nanozyme catalytic therapy for cancer treatments has become one of the heated topics, and the therapeutic efficacy is highly correlated with their catalytic efficiency. In this work, three copper-doped CeO supports with various structures as well as crystal facets are developed to realize dual enzyme-mimic catalytic activities, that is superoxide dismutase (SOD) to reduce superoxide radicals to H O and peroxidase (POD) to transform H O to ∙OH. The wire-shaped CeO /Cu-W has the richest surface oxygen vacancies, and a low level of oxygen vacancy (Vo) formation energy, which allows for the elimination of intracellular reactive oxygen spieces (ROS) and continuous transformation to ∙OH with cascade reaction.

Intermediates Regulation via Electron-Deficient Cu Sites for Selective Nitrate-to-Ammonia Electroreduction.

Ammonia (NH ), known as one of the fundamental raw materials for manufacturing commodities such as chemical fertilizers, dyes, ammunitions, pharmaceuticals, and textiles, exhibits a high hydrogen storage capacity of ≈17.75%. Electrochemical nitrate reduction (NO RR) to valuable ammonia at ambient conditions is a promising strategy to facilitate the artificial nitrogen cycle.

Tailoring the catalytic activity and selectivity on CO to C products by the synergistic effect of reactive molecules: A DFT study.

The conversion of CO to CO is one of the crucial pathways in the carbon dioxide reduction reaction (CORR). Iron and nitrogen co-doped carbon matrix (FeN) is a promising catalyst for converting COto CO with excellent activity and selectivity. However, the reactive mechanism of CORR on the FeN catalyst is not fully unveiled.

Unveiling the Accelerated Water Electrolysis Kinetics of Heterostructural Iron-Cobalt-Nickel Sulfides by Probing into Crystalline/Amorphous Interfaces in Stepwise Catalytic Reactions.

Amorphization and crystalline grain boundary engineering are adopted separately in improving the catalytic kinetics for water electrolysis. Yet, the synergistic effect and advance in the cooperated form of crystalline/amorphous interfaces (CAI) have rarely been elucidated insightfully. Herein, a trimetallic FeCo(NiS ) catalyst with numerous CAI (FeCo(NiS ) -C/A) is presented, which shows highly efficient catalytic activity toward both hydrogen and oxygen evolution reactions (HER and OER).

Molybdenum-iron-cobalt oxyhydroxide with rich oxygen vacancies for the oxygen evolution reaction.

The sluggish kinetics of the oxygen evolution reaction (OER) restrains the development of water splitting technologies and the efficiency of producing sustainable resources. To this end, the introduction of iron and molybdenum in catalytic systems has been employed as a crucial strategy for the enhancement of catalytic activity toward the oxygen evolution reaction (OER), but the relationship between catalyst components and catalytic performance is still evasive. In this study, by doping iron and molybdenum into cobalt hydroxide a cation-exchange method, rich oxygen vacancies and active metal centers are introduced to the trimetallic oxyhydroxide, endowing the catalyst with a low overpotential of 223 mV at 10 mA cm, a low Tafel slope of 43.

Green synthesis of DOX-loaded hollow MIL-100 (Fe) nanoparticles for anticancer treatment by targeting mitochondria.

Fe-based metal-organic frameworks (MOFs) are promising drug delivery materials due to their large surface area, high stability, and biocompatibility. However, their drug loading capacity is constrained by their small pore size, and a further improvement in their drug capacity is needed. In this work, we report an effective and green structural modification strategy to improve drug loading capacity for Fe-based MOFs.