Publications by authors named "YePing Min"
Objective: This study aimed to investigate the prognostic impact of completing 30 mL/kg fluid resuscitation within 1 h in elderly septic shock patients.
Methods: This was a multicenter prospective observational cohort study. We applied logistic regression to assess the impact of completing 30 mL/kg fluid resuscitation within 1 h on respiratory support escalation including new-onset mechanical ventilation, bilevel positive airway pressure (BiPAP), and high-flow nasal cannula (HFNC) as well as heart failure (HF).
Article Synopsis
- The study aims to understand how serum exosomes contribute to chronic obstructive pulmonary disease (COPD), focusing on the role of lncRNA TBX2-AS1 in modifying macrophage behavior.
- Researchers used bioinformatics and various lab techniques to analyze gene expression and assess the impact of TBX2-AS1 on macrophage polarization in COPD.
- Findings reveal that TBX2-AS1 from COPD serum promotes harmful M1 macrophage polarization while inhibiting protective M2 polarization, highlighting its potential as a target for COPD diagnosis and treatment strategies.
Background: Polarization of macrophages and miR-7 have been reported to greatly influence the progress of chronic obstructive pulmonary disease (COPD). However, the interaction is unclear. We aimed to investigate the role of miR-7 in the serum exosome of COPD, thus further revealing the underlying mechanism of COPD.
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