miR-155 increases stemness and decitabine resistance in triple-negative breast cancer cells by inhibiting TSPAN5.

Effective therapeutic targets for triple-negative breast cancer (TNBC), a special type of breast cancer (BC) with rapid metastasis and poor prognosis, are lacking, especially for patients with chemotherapy resistance. Decitabine (DCA) is a Food and Drug Administration-approved DNA methyltransferase inhibitor that has been proven effective for the treatment of tumors. However, its antitumor effect in cancer cells is limited by multidrug resistance.

Prevalence, awareness, treatment, control and risk factors of hypertension in the Guangxi Hei Yi Zhuang and Han populations.

Han is the largest nationality and Zhuang is the largest minority among the 56 nationalities in China. Geographically and linguistically, Zhuang can be classified into 43 ethnic subgroups, with the Hei Yi Zhuang Chinese, who live in Napo County bordering northeast Vietnam and comprise a population of 51,655, having the most conservative culture and customs (Hei Yi means "black-clothing" and the Hei Yi Zhuang revere and wear the color black). The determinants of hypertension and its risk factors in this population have not been well-defined.

[Survey on blood pressure and serum lipids in Hei Yi Zhuang Chinese living in Guangxi].

Objective: To investigate the levels of blood pressure and serum lipids, and examine the relationship between hypertension and hyperlipidemia in Hei Yi Zhuang Chinese living in Guangxi.

Methods: A total of 1056 people of Hei Yi Zhuang ethnicity were studied. Blood pressure, body height, body weight, and serum levels of lipids and apolipoprotein were measured.