Factors Associated With Gonioscopy-Assisted Transluminal Trabeculotomy (GATT) Complications and Failure in Children.

Purpose: To identify the factors associated with the complications and failure of gonioscopy-assisted transluminal trabeculotomy (GATT) in children.

Design: Retrospective case series.

Methods: This study was conducted in an institutional setting in a pediatric population (aged <18 years) who had undergone GATT.

Efficacy and Safety of Aqueous Interleukin-8-Guided Treatment in Cytomegalovirus Retinitis after Bone Marrow Hematopoietic Stem Cell Transplantation.

Purpose: To explore the optimal treatment for cytomegalovirus retinitis (CMVR) in patients status-post Allogeneic bone marrow hematopoietic stem cell transplantation (Allo-HSCT), based on aqueous humor indicators.

Methods: A randomized controlled study with 35 eyes. Eyes were randomized with a 1:1 ratio to standard treatment group (Group 1, with treatment endpoint as aqueous CMV-DNA load＜10 copy/ml), and interleukin (IL)-8 group (Group 2, with treatment endpoint as aqueous IL-8 level ＜30 pg/ml or CMV-DNA load＜10 copy/ml) to receive antiviral intravitreal injections.

Risk Factors for Complications and Failure after Gonioscopy-Assisted Transluminal Trabeculotomy in a Young Cohort.

Purpose: To determine the risk factors for failures and complications of gonioscopy-assisted transluminal trabeculotomy (GATT) in a young cohort.

Design: Retrospective case series.

Participants: Eyes that underwent GATT at Bascom Palmer Eye Institute.

Current Status of Ophthalmology Residency Training in China: The Experience From Well-Structured Centers Around the Country.

Chinese ophthalmology residency training is continuously evolving with an emphasis on standardization. In this article, we assess the current status of ophthalmology residency training in China compared with that in the United States through analysis of literature review and onsite data collection. We comprehensively review various aspects of the residency training structure in China, including accreditation, resident selection, clinical and surgical curricula, research requirements, and evaluation.

Peters plus syndrome and Chorioretinal findings associated with B3GLCT gene mutation - a case report.

Background: Peters plus syndrome (PPS) is a combination of congenital Peters anomaly and systemic abnormalities. It is inherited most commonly in an autosomal recessive pattern with homozygous B3GLCT mutations. Ocular findings consist predominantly anterior segment abnormalities without posterior segment involvement.

Choroidal neovascular membrane associated with primary congenital glaucoma and buphthalmos.

An 18-year-old man with primary congenital glaucoma and buphthalmos in both eyes presented with unilateral, sudden-onset, painless vision loss. He had previously undergone multiple sectoral ab externo rigid-probe trabeculotomy in both eyes and subsequently Baervelt glaucoma implantion in both eyes, with adequate intraocular pressure control. Examination revealed subfoveal choroidal neovascular membrane (CNVM) and associated hemorrhages in the right eye.

Gonioscopy-assisted Transluminal Trabeculotomy (GATT) in Patients With Secondary Open-Angle Glaucoma Following Vitreoretinal Surgery.

Purpose: To examine the short-term efficacy and safety of gonioscopy-assisted transluminal trabeculotomy (GATT) in a series of patients who developed glaucoma following vitreoretinal surgery.

Patients And Methods: Retrospective case series of consecutive patients aged above 18 years with secondary open-angle glaucoma following vitreoretinal surgery who had undergone GATT between January 2015 and June 2019. Eyes were excluded if there is<1 month of follow-up or glaucoma before vitreoretinal surgery.

Supraciliary Microstent Revision in a Patient With Corneal Edema and Primary Open Angle Glaucoma: A Case Report.

A 56-year-old Hispanic male individual with moderate primary open-angle glaucoma on maximal tolerated topical therapy with recent visual field progression presented with excessive glare due to cataract in the right eye. The patient underwent uncomplicated phacoemulsification with supraciliary microstent implantation. Ten weeks postoperatively, he presented with global Descemet folds and focal corneal edema overlying the CyPass implant despite apparent adequate implant position (1 retention ring visible).

Role of in vivo confocal microscopy in the diagnosis of infectious keratitis.

Purpose: To investigate the utility of in vivo confocal microscopy (IVCM) in the diagnosis of infectious keratitis (IK).

Methods: Retrospective chart review of 46 patients with a final diagnosis of IK were included in the study. All patients received IVCM corneal imaging using the Heidelberg Retinal Tomography III system.

Reduction of Acanthamoeba Cyst Density Associated With Treatment Detected by In Vivo Confocal Microscopy in Acanthamoeba Keratitis.

Purpose: Acanthamoeba keratitis (AK) is a severe vision-threatening ocular infection that is frequently a diagnostic challenge. Treatment course is lengthy and often not fully effective. Contact lens wear has been recognized as the prime risk factor for AK.

Association of Dietary Fatty Acid Intake With Glaucoma in the United States.

Importance: Identifying whether an association exists between daily dietary polyunsaturated fatty acid (PUFA) consumption and the prevalence of glaucoma in the United States may provide modifiable dietary risk factors for the development of glaucoma.

Objective: To analyze the association between glaucoma and daily dietary intake of PUFAs, including ω-3 fatty acids, in the US population.

Design, Setting, And Participants: Data from 3865 participants in the National Health and Nutrition Examination Survey (NHANES) 2005-2008 database who were 40 years or older, had participated in the vision health and dietary intake questionnaires, and had available results from laboratory tests and eye examinations that included frequency-doubling technology visual field loss detection tests and optic disc photographs were included.

Severe bilateral optic nerve and retinal hypoperfusion in a patient with acute respiratory distress syndrome and septic shock.

Purpose: To report a case of bilateral central retinal artery occlusion with both anterior and posterior ischemic optic neuropathy.

Observations: A 65-year-old Caucasian woman presented with acute respiratory distress syndrome and septic shock. After treatment with vasopressors and prolonged prone positioning, she was noted to be bilaterally completely blind on hospitalization day 12.

Oral Contraceptive Use and Prevalence of Self-Reported Glaucoma or Ocular Hypertension in the United States.

Purpose: To investigate the association between oral contraceptive (OC) use and glaucoma prevalence in the United States.

Design: Cross-sectional study.

Participants: A total of 3406 female participants, aged 40 years or older, from the 2005 to 2008 National Health and Nutrition Examination Survey, who reported a presence or absence of glaucoma or ocular hypertension completed both the vision and the reproductive health questionnaires and underwent eye examinations.

Prevalence and characteristics of plateau iris configuration among American Caucasian, American Chinese and mainland Chinese subjects.

Background: To investigate the prevalence, risk factors and characteristics of plateau iris configuration (PIC) among American Caucasian, American Chinese and mainland Chinese.

Methods: This multicentre, cross-sectional study of non-glaucomatous subjects (40-80 years) included 111 American Caucasian, 116 American Chinese and 110 mainland Chinese. Prevalence of PIC based on ultrasound biomicroscopy imaging was compared among the different ethnic groups.

Comparison of factors associated with occludable angle between american Caucasians and ethnic Chinese.

Purpose: To determine if factors associated with gonioscopy-determined occludable angle among American Caucasians are similar to those found in ethnic Chinese.

Methods: This is a prospective cross-sectional study with 120 American Caucasian, 116 American Chinese, and 116 mainland Chinese subjects. All three groups were matched for sex and age (40-80 years).

Comparison of iris insertion classification among american caucasian and ethnic Chinese using ultrasound biomicroscopy.

Purpose: To qualitatively classify and compare types of iris insertion among American Caucasians, American Chinese, and mainland Chinese.

Methods: Prospective multicenter cross-sectional study. Sex- and age-matched Caucasian, American Chinese, and mainland Chinese cohorts were enrolled.

The Ig1/2 domain of MuSK binds to muscle surface and is involved in acetylcholine receptor clustering.

The neuromuscular junction, the synapse between motor neurons and muscle cells, serves as an excellent model for studying synapse formation. Agrin is believed to be released by motor neurons to induce postsynaptic differentiation at the neuromuscular junction. MuSK, a receptor tyrosine kinase, appears to be a key component of the agrin receptor complex.