Synopsis of recent research by authors named "Ye Bill Huang"
- Ye Bill Huang's research primarily focuses on the mechanical properties and tableting behavior of amorphous solid dispersions (ASDs) in pharmaceutical applications, particularly studying formulations involving acetaminophen (APAP) and copovidone.
- The findings indicate that varying drug loading levels and moisture content in ASDs significantly impact their mechanical and thermal properties, highlighting a complex relationship between composition and behavior.
- Specifically, the results suggest that while the glass transition temperature (Tg) of ASDs decreases with increased APAP concentration, their hardness initially increases at low concentrations before declining at higher levels, indicating nuanced formulation challenges for drug delivery systems.
