Publications by authors named "Yazun Liu"
Background: The reference values of eNO have certain differences among people of different countries and races. We aimed to obtain the reference value of eNO in healthy children and adolescents (6-18 years old) in China and to explore the associations between the reference values with ages, gender, heights, BMI, and regions.
Methods: We measured FeNO levels in 5949 healthy Chinese children and adolescents, FeNO and CaNO levels in 658 participants from 16 provinces of 7 administrative areas in China aged 6-18.
Amygdalin Improves Allergic Asthma via the Thymic Stromal Lymphopoietin-dendritic Cell-OX40 Ligand Axis in a Mouse Model.
Iran J Allergy Asthma Immunol
October 2023
Asthma, characterized by persistent inflammation and increased sensitivity of the airway, is the most common chronic condition among children. Novel, safe, and reliable treatment strategies are the focus of current research on pediatric asthma. Amygdalin, mainly present in bitter almonds, has anti-inflammatory and immunoregulatory potential, but its effect on asthma remains uninvestigated.
View Article and Find Full Text PDFComplex interplay of gut microbiota between obesity and asthma in children.
Front Microbiol
November 2023
Article Synopsis
- Obesity is a significant risk factor for childhood asthma and is associated with a more severe form of the disease known as obesity-related asthma, which leads to poorer disease management and quality of life.
- The gut microbiota's establishment in early life is crucial for metabolic balance and immune development, with disruptions (dysbiosis) linked to increased risk of obesity and asthma in children.
- This review highlights recent findings on the connection between asthma and obesity, emphasizing the gut microbiota's role in obesity-related asthma, and aims to contribute to future therapeutic strategies.
Objectives: This study aimed to identify the related risk factors and potential predictors of SARS-CoV-2 RNA negative conversion by describing the dynamics of viral shedding in infected children admitted to two hospitals from Shanghai during the Omicron variant outbreak.
Methods: This retrospective cohort included laboratory-confirmed cases of SARS-CoV-2 infection from Shanghai between March 28 and May 31, 2022. Clinical characteristics, personal vaccination, and household vaccination rates were collected through electronic health records and telephone interviews.
Objectives: To describe the epidemiological, clinical, and household transmission characteristics of pediatric COVID-19 cases in Shanghai, China.
Methods: Pediatric patients with COVID-19 hospitalized in Shanghai from March-May 2022 were enrolled in this retrospective, multicenter cohort study. The symptoms and the risk factors associated with disease severity were analyzed.
Management experience of a designated hospital for children with coronavirus disease 2019.
Zhongguo Dang Dai Er Ke Za Zhi
August 2022
The global pandemic of coronavirus disease 2019 (COVID-19) has brought great challenges to the traditional medical model. During the outbreak of COVID-19 in Shanghai, China, from March to May, 2022, there was a significant increase in the number of pediatric cases due to high transmissibility, immune escape, and vaccine breakthrough capacity of Omicron variants. The designated hospitals for children with COVID-19 served as a connecting link between children's specialized hospitals and mobile cabin hospitals.
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