[Regional Differences and Spatial Spillover Effects of Urban Carbon Emission Efficiency in Yangtze River Delta, China].

Based on the super-efficiency SBM model with unexpected output, this study calculated the urban carbon emission efficiency in order to study the regional differences and spatial spillover effects of urban carbon emission efficiency in the Yangtze River Delta. From 2001 to 2020, the highest average of urban carbon emission efficiency in the Yangtze River Delta was only 0.698, with a low overall level and a flat "Inverted-U" evolution trend.

[Prediction of mechanism of ginger-processed Anemarrhenae Rhizoma in intervening in cough due to cold and dampness in lung based on network pharmacology].

This study employed network pharmacology, molecular docking, and animal experiments to investigate the mechanism of ginger-processed Anemarrhenae Rhizoma in treating cough due to cold and dampness in lung, aiming to provide a modern pharmacological basis for this therapy. The active ingredients of ginger-processed Anemarrhenae Rhizoma were retrieved from the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform(TCMSP) with the oral bioavailability(OB≥30%) and drug likeness(DL≥0.18) as the screening conditions and from the relevant literature.

[Evaluation of Land Ecological Status and Diagnosis of Obstacle Factors in Jiangsu, China].

By constructing a land ecological evaluation index system at the village scale and using models such as spatial correlation analysis, hotspot analysis, and obstacle factor diagnosis, the basic characteristics, spatial differentiation, and obstacle factors of land ecological status in Jiangsu Province were studied. This study sought to clarify the foundation, structure, function, and benefit characteristics of land ecosystems and optimize land management and policy regulation. The results showed that： ① The spatial distribution of land ecological status in Jiangsu Province was high in the north and low in the south, with multiple high-value areas radiating outward and decreasing, with low value centers radiating outward and increasing.

Nuclear membrane: A key potential therapeutic target for lipid metabolism.

Lipid homeostasis plays a pivotal role in cellular growth, necessitating the engagement of numerous lipid metabolism genes and the cohesive functioning of organelles. While the nucleus is traditionally recognized for its genetic roles, emerging evidence highlights its significant contribution to lipid homeostasis maintenance. Certain nuclear membrane proteins or associated proteins have the capacity to directly catalyze lipid synthesis or modification processes.

Association between cMIND diet and hypertension among older adults in China: a nationwide survey.

Background: Existing research indicates that the Mediterranean diet has a positive impact on preventing and treating hypertension. However, its specific effect on hypertension among elderly Chinese individuals is unclear.

Aims: The objective of this research was to explore the association between the Chinese version of the Mediterranean-DASH Intervention for Neurodegenerative Delay (cMIND) diet and hypertension among elderly Chinese individuals, aiming to offer novel strategies for alleviating the burden of hypertension in this demographic.

Dynamic evolutionary characteristics and influence mechanisms of carbon emission intensity in counties of the Yangtze River Delta, China.

Clarifying the intrinsic mechanism of county carbon emission intensity (CEI) is essential for guiding the realization of a low-carbon economy as well as for the strategic goals of carbon peaking and carbon neutrality. However, at present, scholars mostly focus on provincial and city scales, with the identification of influencing factors and spatial effect mechanisms of CEI rarely included in the analysis framework. Herein, with the help of three spatial weight matrices, the spatial autocorrelation, the "F + S" influence factor identification method, and the spatial panel econometric model were used to analyze the evolutionary paths and influencing factors of CEI for 209 counties in the Yangtze River Delta (YRD) from 2007 to 2020.

Spatial correlation and coupling between industrial enterprise agglomeration and water pollutant discharge.

Industrial wastewater discharge has become the main cause of water pollution in China. However, the spatial interaction mechanism between industrial structure and water pollution is still unclear. Accordingly, we evaluated and analyzed spatiotemporal changes of the agglomeration pattern of pollution-intensive industrial enterprises and the evolution of the water environmental pollution pattern, as well as the correlation between them.

Coordinated Evolution and Influencing Factors of Population and Economy in the Yangtze River Economic Belt.

The degree of population-economy coupling and coordination is an important indicator of a region's balanced development. This study examines the evolution of the population-economy coupling coordination pattern in the Yangtze River Economic Belt spanning from 2000 to 2019. It draws from the economic growth stage and related theories, and employs methods such as geographic concentration, center of gravity analysis, and the coupling coordination model.

Comprehensive efficiency evaluation of wastewater treatment plants in northeast Qinghai-Tibet Plateau using slack-based data envelopment analysis.

Comprehensive efficiency analysis of wastewater treatment plants (WWPTs) in the alpine region with harsh environment and poor techniques as well as managing experience could provide targeted and effective improvement evidences for local wastewater treatment industry and help to improve the water quality of downstream reaches. In this paper, slack-based data envelopment analysis (SBM-DEA) was adopted to assess the operating efficiencies of WWPTs in northeast Qinghai-Tibet Plateau (QTP). Results showed that the average efficiency score for all WWPTs was 0.

Responses of soil greenhouse gas emissions to land use conversion and reversion-A global meta-analysis.

Exploring the responses of greenhouse gas (GHG) emissions to land use conversion or reversion is significant for taking effective land use measures to alleviate global warming. A global meta-analysis was conducted to analyze the responses of carbon dioxide (CO ), methane (CH ), and nitrous oxide (N O) emissions to land use conversion or reversion, and determine their temporal evolution, driving factors, and potential mechanisms. Our results showed that CH and N O responded positively to land use conversion while CO responded negatively to the changes from natural herb and secondary forest to plantation.

Palbociclib regulates the expression of dihydrofolate reductase and the cell cycle to inhibit t (11;14) multiple myeloma.

Background: Multiple myeloma (MM) with t (11;14) has a unique biology. New combinations of novel agents are needed to improve the prognosis of patients with t (11;14) MM. As a selective inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6), palbociclib (PAL) has been used to treat various malignancies, including breast cancer, ovarian cancer, and so on.

Research on Expansion Characteristics of Aquaculture Ponds and Variations in Ecosystem Service Value from the Perspective of Protecting Cultivated Lands: A Case Study of Liyang City, China.

In the context of global food insecurity, a large amount of cultivated land in China has been occupied by aquaculture ponds, leading to a series of variations in the ecological environment. The Chinese government pays close attention to the problem. In order to achieve sustainable development and ensure the safety of China's cultivated land, the paper uses Liyang City as an example to discuss the spatial characteristics of the expansion of aquaculture ponds through occupying cultivated lands and analyzes the variations in ecosystem service value and cultivated land function.

Spatial temporal patterns and driving factors of industrial pollution and structures in the Yangtze River Economic Belt.

The conflict between industrial development and environmental pollution is global. This study quantitatively analyzes the temporal and spatial changes, spatial effects and determinants of industrial pollution discharge in the Yangtze River Economic Belt through two main indicators: wastewater and SO. Analyze the spatial coupling relationship between industrial agglomeration and pollution emission and the characteristics of industrial structure in different regions.

Antibacterial Effect of Phenolic Acids Derived from Rice Straw and in Combination with Antibiotics Against Escherichia coli.

Many studies have demonstrated that natural plant extracts have inhibitory effects on microorganisms. The purpose of this study was to investigate the inhibitory effect of phenolic acids from rice straw (PAs) on Escherichia coli and their synergistic effect in combination with antibiotics. PAs can inhibit the growth of E.

Analysis of spatio-temporal distribution characteristics and socioeconomic drivers of urban air quality in China.

Having high spatio-temporal resolution data of pollutants is critical to understand environmental pollution patterns and their mechanisms. Our research employs the hourly average concentration data on the air quality index (AQI) and its six component pollutants (PM, PM, SO, NO, CO, and O) in 336 Chinese cities from 2014 to 2019. We analyze annual, seasonal, monthly, hourly, and spatial variations of different air pollutants and their socioeconomic factors.

Utilization of straw-based phenolic acids as a biofugicide for a green agricultural production.

Phenolic compounds inhibit phytopathogenic fungal infections effectively. In this study, the antifungal effects of rice straw-derived phenolic acids (PAs) against Fusarium oxysporum were investigated. PAs can inhibit hyphal growth and spore germination, and p-coumaric acid (CA) is the main antifungal substance in PAs.

Spatial distribution and source analysis of heavy metals in soils influenced by industrial enterprise distribution: Case study in Jiangsu Province.

Heavy metal pollution is frequent in China and has received increasing attention globally. This study investigated the influence of Chinese industrialization and urbanization on soil environmental quality. Soil samples from Jiangsu Province were collected, the Cd, Pb, Cr, Cu, Zn, Hg, and As contents were measured, and their spatial variability structure, spatial distribution pattern, and pollution degree were analyzed.

Simultaneous production of cellulase and ferulic acid esterase by Penicillium decumbens with rice straw as the sole carbon source.

As well as cellulose and hemicelluloses, rice straw contains phenolic acids. The simultaneous production of monosaccharides and phenolic acids could improve the value of rice straw. In this study, it was confirmed that Penicillium decumbens produces more ferulic acid esterase (FAE) than other cellulase-producing fungi.

Spatial-Temporal Evolution of PM Concentration and its Socioeconomic Influence Factors in Chinese Cities in 2014⁻2017.

PM is a main source of China's frequent air pollution. Using real-time monitoring of PM data in 338 Chinese cities during 2014⁻2017, this study employed multi-temporal and multi-spatial scale statistical analysis to reveal the temporal and spatial characteristics of PM patterns and a spatial econometric model to quantify the socio-economic driving factors of PM concentration changes. The results are as follows: (1) The annual average value of PM concentration decreased year by year and the monthly average showed a U-shaped curve from January to December.

The effect of hydroxy safflower yellow A on coronary heart disease through Bcl-2/Bax and PPAR-γ.

The aim of the present study was to investigate the effect of hydroxy safflower yellow A (HSYA) on coronary heart disease through assessing the expression of B-cell lymphoma 2 (Bcl-2)/Bcl-2-like protein 4 (Bax) and peroxisome proliferator-activated receptor (PPAR)-γ. Coronary heart disease was induced in male Bama miniature swines via thoracoscope to serve as an animal model. Coronary heart disease swine were lavaged with 20 or 40 mg/kg HSYA.

Environmental Iodine Content, Female Sex and Age Are Associated with New-Onset Amiodarone-Induced Hypothyroidism: A Systematic Review and Meta-Analysis of Adverse Reactions of Amiodarone on the Thyroid.

Objectives: To investigate the incidence of new-onset amiodarone-induced hypothyroidism (AIH) and the associated risk factors.

Methods: We performed a systematic search in MEDLINE, Embase, the Cochrane Library and the Chinese database from 1995 to 2015. Studies that investigated amiodarone-related adverse reactions on the thyroid were included.

Cholesterol consumption and risk of endometrial cancer: a systematic review and dose-response meta-analysis of observational studies.

In vivo and in vitro studies have indicated the link of cholesterol consumption and endometrial cancer risk, however, previous observational studies have yielded inconsistent results. Additionally, a previous meta-analysis published in 2007 found limited evidence of aforementioned association. Therefore, we performed the dose-response meta-analysis to address this concern.

History of diabetes mellitus is associated with elevated cardiac troponin I levels in patients with chest pain but no coronary heart disease.

Background: The factors and the mechanism contributing to an increase in cardiac troponin I (cTnI) in patients with chest pain, at least one cardiovascular risk factor, and no evidence of coronary heart disease remains elusive.

Methods: Excluding patients with acute coronary syndrome and chronic myocardial isch-emia, we selected 362 consecutive patients with normal coronary angiography or computed tomography coronary angiography results or lesions causing < 50% stenosis in any of the coronary arteries from January 2012 to June 2015. Using a cut-off value of 0.

Dietary fatty acids intake and endometrial cancer risk: a dose-response meta-analysis of epidemiological studies.

Epidemiological studies have provided controversial evidence of the association between dietary fatty acids intake and endometrial cancer risk. The continuous update project of World Cancer Research Fund failed to focus on this issue. To address this inconsistency, we conducted this dose-response meta-analysis based on epidemiological studies published up to the end of June 2015 identified from PubMed, EMBASE and Web of Science.

Fish consumption and risk of myeloma: a meta-analysis of epidemiological studies.

Purpose: The relationship between fish consumption and multiple myeloma (MM) risk has not been consistent across epidemiological studies. We quantitatively assessed the aforementioned association through a systematic review and meta-analysis.

Methods: PubMed was searched through the end of March 2015 for eligible studies.