Mn/Eu co-doped fluoride toward a blue light-excited optical fiber thermometer.

The ongoing development of ratiometric optical thermometry is mainly trapped in thermally coupled levels of rare-earth ions and inefficient ultraviolet excitation. Herein, a new-type multiple sharp line emitting, blue light-excited KNaInF:Mn, Eu fluoride phosphor has been reported as a ratiometric thermometer. The f-f transition of Eu paves a steady reference to a highly temperature sensitive Mnd-d transition and enables high relative sensitivity of 1.

Millimeter-Sized KMnF:Si, NH Red-Luminescent Crystals with High Absorption Efficiency (AE of 93.5%) and External Quantum Efficiency (EQE of 68.9%) Grown by Cooling-Induced Crystallization.

Luminescent bulk crystals exhibit fewer grain boundaries and defects compared with conventional microsized powdery ones. Herein, targeting Mn-activated fluoride crystals with a sharp line-type red luminescence spectrum, we propose a new cooling-induced crystallization method to grow the fluoride crystals. By this new method, we successfully grew millimeter-sized KMnF:Si, NH crystals, featuring an AE (absorption efficiency) of 93.

Stable Polyhedron-Cluster-Based Rigid Fluoride Framework toward Zero-Thermal-Quenching Near-Infrared Emission for Prolonged LED Applications.

Development of highly thermally stable broadband near-infrared (NIR) luminescence materials is crucial for advancing the prolonged stable application of smart NIR light sources. In this study, a zero-thermal-quenching and reversible temperature-dependent broadband NIR-emitting CsNaAlF:Cr phosphor is demonstrated, benefiting from its stable polyhedron-cluster-building rigid structure. The excellent thermal stability of CsNaAlF:Cr is rooted in its stable [AlNaF] cluster building unit, which provides a rigid structure with a weak electron-phonon coupling effect and a wide band gap with a huge thermal activated barrier.

Ion Substitution Strategy toward High-Efficiency Near-Infrared Photoluminescence of CsKInAlF:Cr Solid Solutions.

The rising demand for portable near-infrared (NIR) light sources has accelerated the exploration of NIR luminescent materials with high efficiency and excellent thermal stability. Inspired by the structural-modulated ion substitution strategy, herein, a high-performance CsKInAlF:0.1Cr phosphor with a peak at 794 nm and full width at half-maximum (fwhm) of 117 nm was successfully synthesized by introducing Al ions.

Crosstalk of necroptosis and pyroptosis defines tumor microenvironment characterization and predicts prognosis in clear cell renal carcinoma.

Pyroptosis and necroptosis are two recently identified forms of immunogenic cell death in the tumor microenvironment (TME), indicating a crucial involvement in tumor metastasis. However, the characteristics of necroptosis and pyroptosis that define tumor microenvironment and prognosis in ccRCC patients remain unknown. We systematically investigated the transcriptional variation and expression patterns of Necroptosis and Pyroptosis related genes (NPRGs).

Luminescence properties of Cr-doped near-infrared emissive fluoroyttrates for light-emitting diodes.

In this work, a series of Cr-doped ANaYF (denoted as ANYF:Cr; A = K, Rb, and Cs) fluoroyttrate double-perovskites with broad blue excitation and near-infrared (NIR) emission bands were prepared using a high-temperature solid-state reaction method. The physicochemical and spectroscopic properties of the as-prepared products, including crystal structure, bandgap, morphology, luminescence behaviour and optical performance, were studied in detail. The results show that the Cr activators undergo a decreasing crystal field in ANYF in the direction from K to Cs, yielding a red shift of the emission peak position from 758 to 786 nm, whilst the full-width-at-half-maximum (FWHM) expands from 98 to 104 nm.

IL-25 ameliorates acute cholestatic liver injury via promoting hepatic bile acid secretion.

Cholestasis caused by bile secretion and excretion disorders is a serious manifestation of hepatopathy. Interleukin (IL)-25 is a member of the IL-17 cytokine family, which involves in mucosal immunity and type 2 immunity via its receptor-IL-17RB. Our previous studies have shown that IL-25 improves non-alcoholic fatty liver via stimulating M2 macrophage polarization and promotes development of hepatocellular carcinoma via alternative activation of macrophages.

Interstitial Li Occupancy Enabling Radiative/Nonradiative Transition Control toward Highly Efficient Cr-Based Near-Infrared Luminescence.

Highly efficient and stable broadband near-infrared (NIR) emission phosphors are crucial for the construction of next-generation smart lighting sources; however, the discovery of target phosphors remains a great challenge. Benefiting from the interstitial Li occupancy-induced relatively large distorted octahedral environment for Cr and suppressed nonradiative relaxation of the emission centers, an NIR emission fluoride phosphor NaGaF:Cr,Li peaking at 758 nm with a high internal quantum efficiency of 95.8% and an external quantum efficiency of 38.

Mn-activated dual-wavelength emitting materials toward wearable optical fibre temperature sensor.

Photothermal sensing is crucial for the creation of smart wearable devices. However, the discovery of luminescent materials with suitable dual-wavelength emissions is a great challenge for the construction of stable wearable optical fibre temperature sensors. Benefiting from the Mn-Mn superexchange interactions, a dual-wavelength (530/650 nm)-emitting material LiZnSiO:Mn is presented via simple increasing the Mn concentration, wherein the two emission bands have different temperature-dependent emission behaviours, but exhibit quite similar excitation spectra.

Mn non-equivalent doped fluoride phosphors with a short fluorescence decay time for backlighting.

The non-equivalent doping of Mn in red-emitting fluoride phosphors effectively shortens the fluorescence lifetime. Herein, we successfully synthesized RbNaInF:Mn phosphors by an ion-exchange method. The compensation mechanism of Mn local symmetry and charge balance in the phosphor were studied in detail by theoretical calculations based on density functional theory.

Defect-related luminescence behavior of a Mn non-equivalently doped fluoroantimonate red phosphor.

Non-equivalent or non-octahedral substitution is a crucial strategy to gain Mn-doped fluoride red phosphors with a short fluorescence lifetime, whereas the impact of their structural defects on the photoluminescence (PL) properties remains unrevealed. Here, a non-equivalently doped RbSbF:Mn (RSFM) with a high quantum efficiency of 88% and a thermal stability of 121% at 425 K is newly reported to probe the defect-related PL behavior. Formation energy calculations imply that an interstitial defect was formed to balance the charge and stabilize the crystal structure.

Ultraintense Zero-Phonon Line from a Mn Red-Emitting Phosphor for High-Quality Backlight Display Applications.

The zero-phonon line (ZPL) of Mn, which highly depends on its local environment, is usually much weaker than the vibrational phonon sidebands. In this work, an ultraintense ZPL emission, coming from a brand new red-emitting RbLiGaF:Mn (RLGFM) phosphor upon blue light excitation, is presented. The interesting spectral characteristic originates from the nonequivalent substitution of Mn for Ga in a rigid octahedral structure with a low symmetry, which induces neighboring cation vacancies that distort the local symmetry of the [MnF] octahedra.

Luminescence Enhancement of Mn-Activated Fluorides via a Heterovalent Co-Doping Strategy for Monochromatic Multiplexing.

Mn non-equivalent doped fluorides with high color purity red emission and relatively short decay time are crucial for wide color gamut displays and emerging applications, whereas the low quantum efficiency (QE) restrains their further applications. Herein, the luminescence of Mn non-equivalent doped fluoride KNaAlF:Mn (KNAF:Mn) is significantly enhanced via a heterovalent co-doping strategy, where the luminescence intensity is obviously increased by ∼85%, but the decay time is almost unchanged. The experimental characterization and density functional theory (DFT) calculations provide an understanding of the luminescence enhancement mechanism of heterovalent co-doping, which is enabled by simultaneously improving the stability of Mn and reducing the number of quenching centers (defects and impurities).

Dipole-Orientation-Dependent Förster Resonance Energy Transfer from Aromatic Head Groups to MnBr Blocks in Organic-Inorganic Hybrids.

The understanding and visualization of dipole-dipole interaction on molecular scale are scientifically fundamental and extremely of interest. Herein, two new zero-dimensional (0D) Mn hybrids with aromatic groups and alkyl as organic spacers are selected as models. It was found that the dipole interaction between groups and Mn blocks could have a huge impact on their crystalline structures as well as the luminescent properties.

Structure and luminescence behaviour of a novel red-emitting fluoroperovskite for display backlight application.

In this work, we present a brand-new narrowband red-emitting fluoroperovskite via the introduction of Mn into NaZnF through a facile co-precipitation method at room temperature. The physicochemical properties of the fluoroperovskite such as crystal and electronic structures, morphology, and elemental composition, as well as its spectroscopic properties such as luminescence behaviours and optical performance were characterized and investigated in detail. Evidence shows that NaZnF:Mn exhibits a uniform particulate shape with single-phase crystallinity.

Glass crystallization making red phosphor for high-power warm white lighting.

Rapid development of solid-state lighting technology requires new materials with highly efficient and stable luminescence, and especially relies on blue light pumped red phosphors for improved light quality. Herein, we discovered an unprecedented red-emitting MgAlSiO:Eu composite phosphor (λ = 450 nm, λ = 620 nm) via the crystallization of MgO-AlO-SiO aluminosilicate glass. Combined experimental measurement and first-principles calculations verify that Eu dopants insert at the vacant channel of MgAlSiO crystal with six-fold coordination responsible for the peculiar red emission.

Single-Crystal Red Phosphors and Their Core-Shell Structure for Improved Water-Resistance for Laser Diodes Applications.

A solvent-vapor transport route produces centimeter-sized single-crystal red phosphors. The epitaxial growth route to yield its core-shell structure at ambient temperature was adopted. These red phosphors could be applied in all-inorganic WLED devices.

Silencing c-Myc Enhances the Antitumor Activity of Bufalin by Suppressing the HIF-1α/SDF-1/CXCR4 Pathway in Pancreatic Cancer Cells.

Background: Pancreatic cancer is one of the most aggressive malignancies. Bufalin, a traditional Chinese medicine, has been used to treat pancreatic cancer as an antitumor agent although the mechanism by which it exerts its effects is still unclear. c-Myc has been found to be overexpressed in more than half of human cancers including pancreatic cancer.

In Situ Compositing CsPbBr with Exfoliated Layered-Perovskite CsCaTaO: Interfacial Interaction and Enhanced Stability.

Cesium lead halide (CsPbX, X = Cl, Br, I) perovskite quantum dots (QDs) have been intriguing optoelectronic materials for applications in various devices owing to their superior electronic and optical properties. However, poor resistance to humidity and light irradiation impedes their promotion. Herein, bulk perovskite-type layered CsCaTaO is exfoliated into two-dimensional (2D) negatively charged CaTaO (CTO) nanosheets as seeds to in situ synthesize and composite CsPbBr.

Divalent europium-doped near-infrared-emitting phosphor for light-emitting diodes.

Near-infrared luminescent materials exhibit unique photophysical properties that make them crucial components in photonic, optoelectronic and biological applications. As broadband near infrared phosphors activated by transition metal elements are already widely reported, there is a challenge for next-generation materials discovery by introducing rare earth activators with 4f-5d transition. Here, we report an unprecedented phosphor KLuSiO:Eu that gives an emission band centered at 740 nm with a full-width at half maximum of 160 nm upon 460 nm blue light excitation.

Long-lived Photon Upconversion Phosphorescence in RbCaF:Mn,Yb and the Dynamic Color Separation Effect.

The development of luminescence materials with long-lived upconversion (UC) phosphorescence and long luminescence rise edge (LRE) is a great challenge to advance the technology of photonics and materials sciences. The lanthanide ions-doped UC materials normally possess limited UC lifetime and short LRE, restricting direct afterglow viewing in visual images by the naked eye. Here, we show that the RbCaF:Mn,Yb UC luminescence material generates a long UC lifetime of ∼62 ms peaking at 565 nm and an ultralong LRE of ∼5.

Silencing RRM2 inhibits multiple myeloma by targeting the Wnt/β‑catenin signaling pathway.

Ribonucleotide reductase M2 (RRM2) is one of the two subunits that comprise ribonucleotide reductase (RR), the enzyme that catalyzes the conversion of ribonucleotide 5'‑diphosphates into 2'‑deoxyribonucleotides, which are required for DNA synthesis. RRM2 is a stress response factor important for the development of several tumors. However, its role in multiple myeloma (MM) remains to be fully elucidated.

Emerging ultra-narrow-band cyan-emitting phosphor for white LEDs with enhanced color rendition.

Phosphor-converted white LEDs rely on combining a blue-emitting InGaN chip with yellow and red-emitting luminescent materials. The discovery of cyan-emitting (470-500 nm) phosphors is a challenge to compensate for the spectral gap and produce full-spectrum white light. NaKLiSiO:Eu (NKLSO:Eu) phosphor was developed with impressive properties, providing cyan emission at 486 nm with a narrow full width at half maximum (FWHM) of only 20.