Publications by authors named "Yayoi Maruoka"
J Biomol Struct Dyn
February 2018
Article Synopsis
- Oct4 is essential for maintaining pluripotency in cells and plays important roles in differentiation, uniquely functioning without substitutes from its protein family.
- The nuclear transport of Oct4, which involves importin α, is crucial for its role in reprogramming but lacks detailed understanding at a molecular level.
- A new model has been developed to explain Oct4's interaction with importin α and DNA, highlighting structural differences that may influence its ability to switch between binding to importin α and DNA efficiently.
