Association between single nucleotide polymorphism of DNA damage repair related genes and radiosensitivity in healthy individuals.

Radiosensitivity in humans can influence radiation-induced normal tissue toxicity. As radiosensitivity has a genetic predisposition, we aimed to investigate the possible association between four single nucleotide polymorphism (SNP) sites and the radiosensitivity in healthy people. We genotyped four selected SNPs: TRIP12 (rs13018957), UIMC1 (rs1700490) and POLN (rs2022302), and analyzed the association between SNP and the radiosensitivity in healthy people.

Effects of Neutron and Gamma Rays Combined Irradiation on the Transcriptional Profile of Human Peripheral Blood.

We studied the effects of neutrons, neutrons and γ rays, and γ rays exposures on the transcription spectrum in human peripheral blood of three healthy adult men. Samples were irradiated with 1.42 Gy 2.

ESTABLISHMENT OF THE IN VITRO DOSE-RESPONSE CALIBRATION CURVE FOR X-RAY-INDUCED MICRONUCLEI IN HUMAN LYMPHOCYTES.

The cytokinesis-block micronucleus assay has proven to be a reliable technique for biological dosimetry. This study aimed to establish the dose-response curve for X-ray-induced micronucleus. Peripheral blood samples from three healthy donors were irradiated with various doses and scoring criteria by the micronuclei (MN) in binucleated cells.

Quantitative Proteomics Analysis of Differentially Expressed Proteins in Serum of Former Uranium Miners by Isobaric Tags for the Relative and Absolute Quantitation.

The carcinogenicity of radon has been convincingly documented through epidemiological studies of underground miners. However, there is a lack of early warning indicators for radon radiation damage. In this study, mixed serum samples of 3 groups were collected from 27 underground uranium miners and seven aboveground miners according to the radiation exposure dose.

MicroRNA profiling in BEAS-2B cells exposed to alpha radiation reveals potential biomarkers for malignant cellular transformation.

The carcinogenicity of radon has been convincingly documented through epidemiological studies of underground miners. The risk of lung cancer from radon exposure is due to the continuous radioactive decay of this gas and subsequent emission of high-energy alpha decay particles. And the bronchial epithelial cells are the main targets of radon exposure.

Triclosan facilitates the recovery of volatile fatty acids from waste activated sludge.

The emergence of triclosan (TCS) in the environment has caused extensive concern, but its role in waste activated sludge (WAS) anaerobic fermentation (AF) is still uncertain. This work investigated the impact of TCS on volatile fatty acids (VFAs) recycling from WAS. The results showed that TCS of 200 mg/kg TSS increased the maximum VFA accumulation from 7284 to 15,083 mg COD/L.

Octylphenol facilitates fermentative volatile fatty acids recovery from waste activated sludge.

The presence of endocrine disruptor compounds (EDCs) in wastewater treatment plants has attracted widespread attention, but their potential impact on anaerobic fermentation of waste activated sludge (WAS) remains unclear. Therefore, this study aims to reveal the effect of typical EDC octylphenol (OP) on the recovery of volatile fatty acids (VFAs) in anaerobic fermentation. The results show that OP has a positive effect on the recovery of VFAs from WAS.

Advances in enhanced volatile fatty acid production from anaerobic fermentation of waste activated sludge.

Low acid production and acid-forming process instability are becoming the major issues to limit the popularization of anaerobic fermentation to produce volatile fatty acid. Considerable research efforts have been made to address these problems, from studying the microorganisms that are primarily responsible for or detrimental to this process, to determining their biochemical pathways and developing mathematical models that facilitate better prediction of process performance to identify the mechanism and optimization of process control. A limited understanding of the complex microbiology and biochemistry of anaerobic fermentation is the primary cause of acid production upset or failure.

Comparison of transcriptional profiles in human lymphocyte cells irradiated with C ion beams at 0-2.0 Gy.

Objective: Heavy ions have contributed to tumor site-specific radiotherapy and are a major health risk for astronauts. The purpose of this study was to investigate the changes in gene expression in peripheral lymphocytes of cancer patients and astronauts exposed to C ions, and identify suitable molecular biomarkers for health monitoring. We also aimed to observe the effects of treatment and the level of damage, by comparing the transcriptional profiles of human lymphocyte cell lines exposed to C ion beams at doses of 0-2.