Exploration of uricase-like activity in Pd@Ir nanosheets and their application in relieving acute gout using self-cascade reaction.

Gout, marked by the deposition of sodium urate crystals in joints and peripheral tissues, presents a considerable health challenge. Recent research has shown a growing interest in nanozyme-based treatments for gout. However, literature on nanozymes that combine uricase-like (UOX) activity for uric acid (UA) degradation with catalase (CAT)-like activity for HO elimination through a self-cascade reaction is limited.

Deciphering the toxicity mechanism of haloquinolines on Chlorella pyrenoidosa using QSAR and metabolomics approaches.

The hazardous potential of haloquinolines (HQLs) is becoming an issue of great concern due to its wide and long-term usage in many personal care products. We examined the growth inhibition, structure-activity relationship, and toxicity mechanism of 33 HQLs on Chlorella pyrenoidosa using the 72-h algal growth inhibition assay, three-dimensional quantitative structure-activity relationship (3D-QSAR), and metabolomics. We found that the IC (half maximal inhibitory concentration) values for 33 compounds ranged from 4.

Allelopathic inhibition effects and mechanism of phenolic acids to Microcystis aeruginosa.

Allelochemicals are essential agents for the biological control of harmful blooms. It is crucial to identify efficient algal suppressors and understand their mechanisms. This study reports the inhibition of Microcystis aeruginosa growth by 6 phenolic acids derived from plants' secondary metabolites.

Single camera 20 kHz two-color formaldehyde PLIF thermometry using a dual-wavelength-switching burst mode laser.

We propose and demonstrate a two-color formaldehyde planar laser induced fluorescence spectroscopy thermometry scheme using the third-harmonic of injection-seeded Nd:YAG lasers. The 28183.5 and 28184.

Dose-effect and structure-activity relationships of haloquinoline toxicity towards Vibrio fischeri.

Many quinoline (QL) derivatives are present in the environment and pose potential threats to human health and ecological safety. The acute toxicity of 30 haloquinolines (HQs) was examined using the photobacterium Vibrio fischeri. IC values (inhibitory concentration for 50% luminescence elimination) were in the range 5.